Human herpesvirus-6 infection and bone marrow transplantation

Tetsushi Yoshikawa, Seiji Kojima, Yoshizo Asano

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Human herpesvirus-6 (HHV-6) is ubiquitous in the human population and causes exanthem subitum, a benign disease seen in infancy. However it also produces a wide spectrum of clinical manifestations including cases with a fatal outcome. The virus remains latent in several organs, including the kidneys, liver, lymph/nodes and salivary glands, after the primary infection and reactivates when immune function is impaired. Reactivation of the virus occurred in a half of the bone marrow recipients 2 to 4 weeks after bone marrow transplantation (BMT). It remains to be established whether HHV-6 in fact causes the fever and rash observed in recipients who have reactivation of the virus. The data reviewed here will be required to compare with those of human herpesvirus 7 and a different group of HHV-6.

Original languageEnglish
Pages (from-to)65-73
Number of pages9
JournalLeukemia and Lymphoma
Volume8
Issue number1-2
DOIs
Publication statusPublished - 01-01-1992

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Human Herpesvirus 6
Herpesviridae Infections
Bone Marrow Transplantation
Viruses
Exanthema
Human Herpesvirus 7
Fatal Outcome
Salivary Glands
Fever
Lymph Nodes
Bone Marrow
Kidney
Liver
Infection
Population

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Yoshikawa, Tetsushi ; Kojima, Seiji ; Asano, Yoshizo. / Human herpesvirus-6 infection and bone marrow transplantation. In: Leukemia and Lymphoma. 1992 ; Vol. 8, No. 1-2. pp. 65-73.
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Human herpesvirus-6 infection and bone marrow transplantation. / Yoshikawa, Tetsushi; Kojima, Seiji; Asano, Yoshizo.

In: Leukemia and Lymphoma, Vol. 8, No. 1-2, 01.01.1992, p. 65-73.

Research output: Contribution to journalArticle

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