Hydroxyurea-induced amyopathic dermatomyositis presenting with heliotrope erythema

Eri Ito, Yoshinao Muro, Akitaka Shibata, Kazumitsu Sugiura, Masashi Akiyama

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Abstract

Hydroxyurea (HU) is a chemotherapeutic agent used for the treatment of myeloproliferative disorders such as chronic myeloid leukemia, polycythemia vera, and essential thrombocytosis. We describe a 69-year-old man who had essential thrombocytosis and developed amyopathic dermatomyositis after long-term HU therapy. He presented with Gottron papules and heliotrope erythema. The former has been described in all cases of HU-induced dermatomyositis; the latter has been seen in a few cases of that disorder.

Original languageEnglish
JournalDermatology Online Journal
Volume20
Issue number8
Publication statusPublished - 2014
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Dermatology

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