Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

Ikuya Tsuge; Yasuto Kondo; Yoichi Nakajima; Noriko Nakagawa; Kohsuke Imai; Shigeaki Nonoyama; Koichi Oshima; Osamu Ohara; Michiyo Hatanaka; Etsuko Kitano; Hajime Kitamura; Atsuo Urisu

Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

Ikuya Tsuge, Yasuto Kondo, Yoichi Nakajima, Noriko Nakagawa, Kohsuke Imai, Shigeaki Nonoyama, Koichi Oshima, Osamu Ohara, Michiyo Hatanaka, Etsuko Kitano, Hajime Kitamura, Atsuo Urisu

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.

Original language	English
Pages (from-to)	558-560
Number of pages	3
Journal	Clinical and Experimental Rheumatology
Volume	28
Issue number	4
Publication status	Published - 2010

All Science Journal Classification (ASJC) codes

Rheumatology
Immunology and Allergy
Immunology

Cite this

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title = "Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease",

abstract = "Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.",

author = "Ikuya Tsuge and Yasuto Kondo and Yoichi Nakajima and Noriko Nakagawa and Kohsuke Imai and Shigeaki Nonoyama and Koichi Oshima and Osamu Ohara and Michiyo Hatanaka and Etsuko Kitano and Hajime Kitamura and Atsuo Urisu",

year = "2010",

language = "English",

volume = "28",

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journal = "Clinical and Experimental Rheumatology",

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TY - JOUR

T1 - Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

AU - Tsuge, Ikuya

AU - Kondo, Yasuto

AU - Nakajima, Yoichi

AU - Nakagawa, Noriko

AU - Imai, Kohsuke

AU - Nonoyama, Shigeaki

AU - Oshima, Koichi

AU - Ohara, Osamu

AU - Hatanaka, Michiyo

AU - Kitano, Etsuko

AU - Kitamura, Hajime

AU - Urisu, Atsuo

PY - 2010

Y1 - 2010

N2 - Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.

AB - Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.

UR - http://www.scopus.com/inward/record.url?scp=79952052780&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952052780&partnerID=8YFLogxK

M3 - Article

C2 - 20810037

AN - SCOPUS:79952052780

SN - 0392-856X

VL - 28

SP - 558

EP - 560

JO - Clinical and Experimental Rheumatology

JF - Clinical and Experimental Rheumatology

IS - 4

ER -

Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

Abstract

All Science Journal Classification (ASJC) codes

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