Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis

Ken Nakamura; Keizo Sugaya; Yasuhiro Nakata; Sayuri Shima; Tatsuro Mutoh; Imaharu Nakano

doi:10.1111/ncn3.130

Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis

Ken Nakamura, Keizo Sugaya, Yasuhiro Nakata, Sayuri Shima, Tatsuro Mutoh, Imaharu Nakano

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6 Citations (Scopus)

Abstract

Relapsing polychondritis is a rare autoimmune multisystem disease characterized by the inflammation of cartilaginous tissues. Neurological complications with relapsing polychondritis are extremely rare. We report an 81-year-old woman with relapsing polychondritis who subsequently developed encephalitis and cognitive impairment. Brain magnetic resonance imaging showed slightly high signal intensity in the bilateral frontal dura mater using fluid-attenuated inversion recovery. T₁-weighted images with contrast enhancement showed abnormal enhancement of the dura mater, indicating hypertrophic pachymeningitis. To our knowledge, this is the first case report of relapsing polychondritis complicated by both hypertrophic pachymeningitis and encephalitis in the absence of other recognizable autoimmune diseases.

Original language	English
Pages (from-to)	42-43
Number of pages	2
Journal	Neurology and Clinical Neuroscience
Volume	3
Issue number	1
DOIs	https://doi.org/10.1111/ncn3.130
Publication status	Published - 01-01-2015

All Science Journal Classification (ASJC) codes

Neurology
Clinical Neurology

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abstract = "Relapsing polychondritis is a rare autoimmune multisystem disease characterized by the inflammation of cartilaginous tissues. Neurological complications with relapsing polychondritis are extremely rare. We report an 81-year-old woman with relapsing polychondritis who subsequently developed encephalitis and cognitive impairment. Brain magnetic resonance imaging showed slightly high signal intensity in the bilateral frontal dura mater using fluid-attenuated inversion recovery. T1-weighted images with contrast enhancement showed abnormal enhancement of the dura mater, indicating hypertrophic pachymeningitis. To our knowledge, this is the first case report of relapsing polychondritis complicated by both hypertrophic pachymeningitis and encephalitis in the absence of other recognizable autoimmune diseases.",

author = "Ken Nakamura and Keizo Sugaya and Yasuhiro Nakata and Sayuri Shima and Tatsuro Mutoh and Imaharu Nakano",

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AU - Nakamura, Ken

AU - Sugaya, Keizo

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AU - Shima, Sayuri

AU - Mutoh, Tatsuro

AU - Nakano, Imaharu

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Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis

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