Hypothalamic hamartoma with neurofibrillary tangles

Seiji Yamada, Christopher P. Wood, Jawad A. Shah, Jonathan Vida, Joseph E. Parisi, Mark E. Jentoft

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Hypothalamic hamartomas are rare tumors that typically present in childhood, often with gelastic seizures, precocious puberty, or as a manifestation of Pallister‑Hall syndrome. Neurofibrillary tangles are cytoplasmic aggregates of hyperphosphorylated tau that are best recognized in Alzheimer disease, other tau-associated neurodegenerative diseases, or as part of aging, but occasionally may be seen in low-grade neoplasms with a ganglion cell component as gangliocytoma or ganglioglioma. Herein, we report a case of hypothalamic hamartoma with neurofibrillary tangles.

Original languageEnglish
Pages (from-to)480-484
Number of pages5
Issue number5
Publication statusPublished - 01-10-2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Clinical Neurology


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