Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand: Evidence for porcine-to-human interspecies transmission

Satoshi Komoto, Ratana Tacharoenmuang, Ratigorn Guntapong, Tomihiko Ide, Phakapun Sinchai, Sompong Upachai, Saori Fukuda, Tetsushi Yoshikawa, Piyanit Tharmaphornpilas, Somchai Sangkitporn, Koki Taniguchi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An unusual rotavirus strain with the G9P[23] genotype (RVA/Human-wt/THA/KKL-117/2014/G9P[23]) was identified in a stool specimen from a 10-month-old child hospitalized with severe diarrhoea. In this study, we sequenced and characterized the complete genome of strain KKL-117. On full-genomic analysis, strain KKL-117 was found to have the following genotype constellation: G9-P[23]-I5-R1-C1-M1-A8-N1-T1-E1-H1. The non-G/P genotype constellation of this strain (I5-R1-C1-M1-A8- N1-T1-E1-H1) is commonly shared with rotavirus strains from pigs. Furthermore, phylogenetic analysis indicated that each of the 11 genes of strain KKL-117 appeared to be of porcine origin. Our observations provide important insights into the dynamic interactions between human and porcine rotavirus strains.

Original languageEnglish
Pages (from-to)532-538
Number of pages7
JournalJournal of General Virology
Volume98
Issue number4
DOIs
Publication statusPublished - 01-04-2017

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Rotavirus
Thailand
Diarrhea
Swine
Genotype
Pyridinolcarbamate
Tacrine
Hospitalized Child
Genome
Genes

All Science Journal Classification (ASJC) codes

  • Virology

Cite this

Komoto, Satoshi ; Tacharoenmuang, Ratana ; Guntapong, Ratigorn ; Ide, Tomihiko ; Sinchai, Phakapun ; Upachai, Sompong ; Fukuda, Saori ; Yoshikawa, Tetsushi ; Tharmaphornpilas, Piyanit ; Sangkitporn, Somchai ; Taniguchi, Koki. / Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand : Evidence for porcine-to-human interspecies transmission. In: Journal of General Virology. 2017 ; Vol. 98, No. 4. pp. 532-538.
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Komoto, S, Tacharoenmuang, R, Guntapong, R, Ide, T, Sinchai, P, Upachai, S, Fukuda, S, Yoshikawa, T, Tharmaphornpilas, P, Sangkitporn, S & Taniguchi, K 2017, 'Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand: Evidence for porcine-to-human interspecies transmission', Journal of General Virology, vol. 98, no. 4, pp. 532-538. https://doi.org/10.1099/jgv.0.000722

Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand : Evidence for porcine-to-human interspecies transmission. / Komoto, Satoshi; Tacharoenmuang, Ratana; Guntapong, Ratigorn; Ide, Tomihiko; Sinchai, Phakapun; Upachai, Sompong; Fukuda, Saori; Yoshikawa, Tetsushi; Tharmaphornpilas, Piyanit; Sangkitporn, Somchai; Taniguchi, Koki.

In: Journal of General Virology, Vol. 98, No. 4, 01.04.2017, p. 532-538.

Research output: Contribution to journalArticle

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T1 - Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand

T2 - Evidence for porcine-to-human interspecies transmission

AU - Komoto, Satoshi

AU - Tacharoenmuang, Ratana

AU - Guntapong, Ratigorn

AU - Ide, Tomihiko

AU - Sinchai, Phakapun

AU - Upachai, Sompong

AU - Fukuda, Saori

AU - Yoshikawa, Tetsushi

AU - Tharmaphornpilas, Piyanit

AU - Sangkitporn, Somchai

AU - Taniguchi, Koki

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