Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes

J. M. Dijkstra, W. Fuchs, T. C. Mettenleiter, B. G. Klupp

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, UL7, UL8, UL8.5, UL9, UL10, UL11, and UL12 protein products of herpes simplex virus type 1. Transcriptional analyses indicated presence of 3'-coterminal mRNAs for genes UL8, UL8.5, and UL9 as well as for genes UL6 and UL7, respectively, while UL10 was represented by a very abundant unique transcript. Both gene arrangement and transcriptional organization within this region of the pseudorabies virus genome thus parallels the situation found in other alphaherpesviruses.

Original languageEnglish
Pages (from-to)17-35
Number of pages19
JournalArchives of Virology
Issue number1
Publication statusPublished - 06-02-1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Virology


Dive into the research topics of 'Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes'. Together they form a unique fingerprint.

Cite this