Idiopathic pulmonary veno-occlusive disease

Mai Iwaki, Kazuyoshi Imaizumi, Toyoharu Yokoi, Masashi Kondo, Katsuhiro Kawaguchi, Yoshinori Hasegawa

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


We report a case of idiopathic pulmonary veno-occlusive disease (PVOD). The patient experienced progressively worsening dyspnea. Heart catheterization revealed severe pulmonary hypertension. High-resolution computed tomography (HRCT) showed diffuse, poorly identified centrilobular ground-glass opacities. Surgical lung biopsy led to the diagnosis of PVOD. A microscopic examination revealed occlusions of pulmonary veins and venules over a wide area with prominent loop-like capillary dilatations. These pathological findings may be correlated with the radiological characteristics of HRCT in this case.

Original languageEnglish
Pages (from-to)1289-1292
Number of pages4
JournalInternal Medicine
Issue number15
Publication statusPublished - 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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