IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia

Koji Matsumoto, Toshiharu Yasugi, Akinori Oki, Takuma Fujii, Chisato Nagata, Souei Sekiya, Hiroshi Hoshiai, Yuji Taketani, Tadahito Kanda, Takashi Kawana, Hiroyuki Yoshikawa

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

To identify the predictive markers for spontaneous regression of cervical intraepithelial neoplasia (CIN), we examined whether IgG antibody responses to common human papillomavirus (HPV) L1-capsids correlate with CIN regression. In a cohort study, a total of 116 Japanese women with CIN grade I/II were tested for cervical HPV DNA and serum IgG antibodies to HPV16/52/58/6 L1-capsids. Our data suggest that baseline IgG reactivities to HPV L1-capsids do not serve as a predictive marker of CIN regression, in contrast to histological CIN grades and HPV DNA status.

Original languageEnglish
Pages (from-to)309-313
Number of pages5
JournalCancer Letters
Volume231
Issue number2
DOIs
Publication statusPublished - 18-01-2006

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia'. Together they form a unique fingerprint.

Cite this