Image evaluation of endolymphatic space in fluctuating hearing loss without vertigo

Masaaki Teranishi, Shinji Naganawa, Naomi Katayama, Makoto Sugiura, Seiichi Nakata, Michihiko Sone, Tsutomu Nakashima

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The objective of the present study was to investigate endolymphatic space images in patients with fluctuating hearing loss without vertigo, and to elucidate its underlying pathophysiology. Eight patients with fluctuating hearing loss without vertigo were included in this study. 3T MRI was taken, 24 h after intratympanic injection of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Electrocochleography and VEMP tests were performed to evaluate cochlear and vestibular functions. Endolymphatic hydrops were observed both in the cochlea and in the vestibule of all eight patients. Three patients out of six whose summating potential/action potential (SP/AP) ratio was recordable showed an elevation of SP/AP ratio. In the two patients with remarkable endolymphatic hydrops in the vestibule, VEMP was absent from the affected ear. In conclusion, 3T MRI after intratympanic injection of Gd-DTPA revealed endolymphatic hydrops both in the cochlea and in the vestibule in the patients with fluctuating hearing loss without vertigo.

Original languageEnglish
Pages (from-to)1871-1877
Number of pages7
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume266
Issue number12
DOIs
Publication statusPublished - 12-2009

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

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