Abstract
Expression of Chromogranin A and C was examined immunohistochemically on 4S surgically obtained pituitary adenomas. Positive rate of chromogranin A was 40.0% and chromogranin C was positive in 8.0% of 4S pituitary adenomas. Chromogranin A was expressed frequently in adenomas in which at least one of the FSH alpha, FSH beta, LH beta and TSH beta subunits was positive. It also expressed frequently in non-functioning adenomas. The positive rate of chromogranin A was low in GH or PRL positive adenomas. These findings suggest that chromogranin could be a parameter of the functional differentiation of the pituitary adenomas.
| Original language | English |
|---|---|
| Pages (from-to) | 626-628 |
| Number of pages | 3 |
| Journal | Pathology Research and Practice |
| Volume | 187 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1991 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Cell Biology
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