TY - JOUR
T1 - Improvement in the nutritional status after transcatheter aortic valve implantation
AU - Tobe, Akihiro
AU - Tanaka, Akihito
AU - Tokuda, Yoshiyuki
AU - Akita, Sho
AU - Miki, Yusuke
AU - Furusawa, Kenji
AU - Ishii, Hideki
AU - Usui, Akihiko
AU - Murohara, Toyoaki
N1 - Funding Information:
This study was supported by a grant from Grant-in-Aid for Scientific Research (KAKENHI) (No. 17K09493) of the Ministry of Education, Culture, Sports, Science and Technology (MEXT) and Japanese Society for the Promotion of Science (JSPA). Hideki Ishii received lecture fees from Astellas Pharma Inc. Astrazeneca Inc. Daiichi-Sankyo Pharma Inc. and MSD K. K. Akihiko Usui received lecture fees from Terumo, Japan Blood Products Organization. Akihiko Usui received unrestricted research grant for Department of Cardiac Surgery, Nagoya University Graduate School of Medicine from Edwards Lifesciences Corporation, Senko Medical Instrument Mfg.Co.Ltd. Medtronic, Terumo, and Lifline. Toyoaki Murohara received lecture fees from Bayel Pharmaceutical Co. Ltd. Daiichi-Sankyo Co. Ltd. Dainippon Sumitomo Pharma Co. Ltd. Kowa Co. Ltd. MSD K. K. Mitsubishi Tanabe Pharma Co. Nippon Boehringer Ingelheim Co. Ltd. Novartis Pharma K. K. Pfizer Japan Inc. Sanofi-aventis K. K. and Takeda Pharmaceutical Co. Ltd. Toyoaki Murohara received unrestricted research grant for Department of Cardiology, Nagoya University Graduate School of Medicine from Astellas Pharma Inc. Daiichi-Sankyo Co. Ltd. Dainippon Sumitomo Pharma Co. Ltd. Kowa Co. Ltd. MSD K. K. Mitsubishi Tanabe Pharma Co. Nippon Boehringer Ingelheim Co. Ltd. Novartis Pharma K. K. Otsuka Pharma Ltd. Pfizer Japan Inc. Sanofi-aventis K. K. Takeda Pharmaceutical Co. Ltd. and Teijin Pharma Ltd. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Funding Information:
This study was supported by a grant from Grant-in-Aid for Scientific Research ( KAKENHI ) (No. 17K09493 ) of the Ministry of Education, Culture, Sports, Science and Technology ( MEXT ) and Japanese Society for the Promotion of Science (JSPA).
Publisher Copyright:
© 2021
PY - 2021/9
Y1 - 2021/9
N2 - Background: A poor nutritional status of patients before transcatheter aortic valve implantation (TAVI) has been reported to be associated with poor clinical outcomes. However, changes in the nutritional status following TAVI have not been fully elucidated. Methods: In this single-center retrospective observational study, 129 patients whose nutritional status at baseline and 6 months after TAVI were available were investigated. The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) were used to assess the nutritional status of the patients at baseline and at 6 months. We further assessed changes in the nutritional status of patients in the subgroups stratified according to the baseline levels as low and high. Results: The PNI and GNRI values at 6 months were significantly better than at baseline [PNI, baseline: 44.5 (41.0–48.0), 6 months: 46.0 (41.9–48.3), p = 0.02; GNRI, baseline: 95.3 (89.0–100.3), 6 months: 97.8 (91.5–101.4), p = 0.006]. Both PNI and GNRI values at 6 months were significantly better in the patients with a low baseline nutritional status, while no significant change was observed in those with high baseline levels [PNI, low; baseline: 36.8 (36.1–39.4), 6 months: 40.8 (39.0–43.4), p = 0.002, high; baseline: 47.0 (43.0–49.5), 6 months: 46.5 (43.5–50.5), p = 0.44 and GNRI, low; baseline: 86.4 (81.7–88.7), 6 months: 88.6 (83.4–95.3), p = 0.001, high; baseline: 99.8 (95.3–102.8), 6 months: 100.7 (96.8–103.4), p = 0.34]. Conclusion: Nutritional status of patients might improve during the chronic phase after TAVI, especially in those with poor baseline levels.
AB - Background: A poor nutritional status of patients before transcatheter aortic valve implantation (TAVI) has been reported to be associated with poor clinical outcomes. However, changes in the nutritional status following TAVI have not been fully elucidated. Methods: In this single-center retrospective observational study, 129 patients whose nutritional status at baseline and 6 months after TAVI were available were investigated. The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) were used to assess the nutritional status of the patients at baseline and at 6 months. We further assessed changes in the nutritional status of patients in the subgroups stratified according to the baseline levels as low and high. Results: The PNI and GNRI values at 6 months were significantly better than at baseline [PNI, baseline: 44.5 (41.0–48.0), 6 months: 46.0 (41.9–48.3), p = 0.02; GNRI, baseline: 95.3 (89.0–100.3), 6 months: 97.8 (91.5–101.4), p = 0.006]. Both PNI and GNRI values at 6 months were significantly better in the patients with a low baseline nutritional status, while no significant change was observed in those with high baseline levels [PNI, low; baseline: 36.8 (36.1–39.4), 6 months: 40.8 (39.0–43.4), p = 0.002, high; baseline: 47.0 (43.0–49.5), 6 months: 46.5 (43.5–50.5), p = 0.44 and GNRI, low; baseline: 86.4 (81.7–88.7), 6 months: 88.6 (83.4–95.3), p = 0.001, high; baseline: 99.8 (95.3–102.8), 6 months: 100.7 (96.8–103.4), p = 0.34]. Conclusion: Nutritional status of patients might improve during the chronic phase after TAVI, especially in those with poor baseline levels.
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U2 - 10.1016/j.jjcc.2021.04.006
DO - 10.1016/j.jjcc.2021.04.006
M3 - Article
C2 - 33992501
AN - SCOPUS:85105700058
VL - 78
SP - 250
EP - 254
JO - Journal of Cardiology
JF - Journal of Cardiology
SN - 0914-5087
IS - 3
ER -