In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi; Masabumi Kato; Tetsushi Taguchi; Shigeto Shimmura; Hideyuki Miyashita; Kazuo Tsubota; Junzo Tanaka

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi
, Masabumi Kato
, Tetsushi Taguchi
, Shigeto Shimmura
, Hideyuki Miyashita
, Kazuo Tsubota
, Junzo Tanaka

Research output: Contribution to conference › Paper › peer-review

Abstract

We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

Original language	English
Pages	2247
Number of pages	1
Publication status	Published - 2005
Externally published	Yes
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 25-05-2005 → 27-05-2005

Conference

Conference	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	25-05-05 → 27-05-05

All Science Journal Classification (ASJC) codes

General Engineering

Cite this

@conference{818d922a5c264445b794babc3210efc9,

title = "In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma",

abstract = "We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.",

keywords = "Artificial cornea, Epithelium, In vivo, Pre-seeded, PVA hydrogel",

author = "Hisatoshi Kobayashi and Masabumi Kato and Tetsushi Taguchi and Shigeto Shimmura and Hideyuki Miyashita and Kazuo Tsubota and Junzo Tanaka",

year = "2005",

language = "English",

pages = "2247",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

}

TY - CONF

T1 - In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

AU - Kobayashi, Hisatoshi

AU - Kato, Masabumi

AU - Taguchi, Tetsushi

AU - Shimmura, Shigeto

AU - Miyashita, Hideyuki

AU - Tsubota, Kazuo

AU - Tanaka, Junzo

PY - 2005

Y1 - 2005

N2 - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

AB - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

KW - Artificial cornea

KW - Epithelium

KW - In vivo

KW - Pre-seeded

KW - PVA hydrogel

UR - https://www.scopus.com/pages/publications/33645646765

UR - https://www.scopus.com/pages/publications/33645646765#tab=citedBy

M3 - Paper

AN - SCOPUS:33645646765

SP - 2247

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Abstract

Conference

All Science Journal Classification (ASJC) codes

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