Indications for sentinel lymph node biopsy in node-negative oral cancers

Taijiro Ozawa; Isao Oze; Takashi Matsuzuka; Eiichi Sasaki; Junkichi Yokoyama; Yoshie Sano; Masayuki Tomifuji; Koji Araki; Yasunao Kogashiwa; Ichiro Tateya; Shinya Agena; Tomohiro Sakashita; Hidenori Tsuzuki; Hoshino Terada; Hidenori Suzuki; Daisuke Nishikawa; Shintarou Beppu; Takuma Matoba; Nobuaki Mukoyama; Keisuke Oguri; Yasuhisa Hasegawa

doi:10.1002/hed.27477

Indications for sentinel lymph node biopsy in node-negative oral cancers

Taijiro Ozawa
, Isao Oze
, Takashi Matsuzuka
, Eiichi Sasaki
, Junkichi Yokoyama
, Yoshie Sano
, Masayuki Tomifuji
, Koji Araki
, Yasunao Kogashiwa
, Ichiro Tateya
, Shinya Agena
, Tomohiro Sakashita
, Hidenori Tsuzuki
, Hoshino Terada
, Hidenori Suzuki
, Daisuke Nishikawa
, Shintarou Beppu
, Takuma Matoba
, Nobuaki Mukoyama
, Keisuke Oguri

Yasuhisa Hasegawa

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes. Methods: The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome. Results: In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3%, 35.3%, and 51.2%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9%. Conclusions: SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.

Original language	English
Pages (from-to)	2533-2543
Number of pages	11
Journal	Head and Neck
Volume	45
Issue number	10
DOIs	https://doi.org/10.1002/hed.27477
Publication status	Published - 10-2023
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Otorhinolaryngology

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10.1002/hed.27477

Cite this

Ozawa, T., Oze, I., Matsuzuka, T., Sasaki, E., Yokoyama, J., Sano, Y., Tomifuji, M., Araki, K., Kogashiwa, Y., Tateya, I., Agena, S., Sakashita, T., Tsuzuki, H., Terada, H., Suzuki, H., Nishikawa, D., Beppu, S., Matoba, T., Mukoyama, N., ... Hasegawa, Y. (2023). Indications for sentinel lymph node biopsy in node-negative oral cancers. Head and Neck, 45(10), 2533-2543. https://doi.org/10.1002/hed.27477

@article{d64ba294f916462ca5f0ca197e033623,

title = "Indications for sentinel lymph node biopsy in node-negative oral cancers",

abstract = "Background: We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes. Methods: The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome. Results: In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3\%, 35.3\%, and 51.2\%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9\%. Conclusions: SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.",

keywords = "indication, neck dissection, node-negative, oral cavity cancer, sentinel lymph node biopsy",

author = "Taijiro Ozawa and Isao Oze and Takashi Matsuzuka and Eiichi Sasaki and Junkichi Yokoyama and Yoshie Sano and Masayuki Tomifuji and Koji Araki and Yasunao Kogashiwa and Ichiro Tateya and Shinya Agena and Tomohiro Sakashita and Hidenori Tsuzuki and Hoshino Terada and Hidenori Suzuki and Daisuke Nishikawa and Shintarou Beppu and Takuma Matoba and Nobuaki Mukoyama and Keisuke Oguri and Yasuhisa Hasegawa",

note = "Publisher Copyright: {\textcopyright} 2023 Wiley Periodicals LLC.",

year = "2023",

month = oct,

doi = "10.1002/hed.27477",

language = "English",

volume = "45",

pages = "2533--2543",

journal = "Head and Neck",

issn = "1043-3074",

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Ozawa, T, Oze, I, Matsuzuka, T, Sasaki, E, Yokoyama, J, Sano, Y, Tomifuji, M, Araki, K, Kogashiwa, Y, Tateya, I, Agena, S, Sakashita, T, Tsuzuki, H, Terada, H, Suzuki, H, Nishikawa, D, Beppu, S, Matoba, T, Mukoyama, N, Oguri, K & Hasegawa, Y 2023, 'Indications for sentinel lymph node biopsy in node-negative oral cancers', Head and Neck, vol. 45, no. 10, pp. 2533-2543. https://doi.org/10.1002/hed.27477

TY - JOUR

T1 - Indications for sentinel lymph node biopsy in node-negative oral cancers

AU - Ozawa, Taijiro

AU - Oze, Isao

AU - Matsuzuka, Takashi

AU - Sasaki, Eiichi

AU - Yokoyama, Junkichi

AU - Sano, Yoshie

AU - Tomifuji, Masayuki

AU - Araki, Koji

AU - Kogashiwa, Yasunao

AU - Tateya, Ichiro

AU - Agena, Shinya

AU - Sakashita, Tomohiro

AU - Tsuzuki, Hidenori

AU - Terada, Hoshino

AU - Suzuki, Hidenori

AU - Nishikawa, Daisuke

AU - Beppu, Shintarou

AU - Matoba, Takuma

AU - Mukoyama, Nobuaki

AU - Oguri, Keisuke

AU - Hasegawa, Yasuhisa

PY - 2023/10

Y1 - 2023/10

N2 - Background: We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes. Methods: The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome. Results: In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3%, 35.3%, and 51.2%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9%. Conclusions: SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.

AB - Background: We aimed to define the indications for sentinel lymph node biopsy (SLNB), the third option for cervical treatment in oral cancer with negative cervical lymph nodes. Methods: The greatest depth of invasion (DOI) and long diameter (LD) of the primary site were used as exposures. SLN metastasis was considered the outcome. Results: In three trials conducted between 2009 and 2016, 158 patients were eligible and reassigned to this study group. The scatterplot based on the respective values of DOI and LD would eventually be divided into three sections. In cases of sections T1, T2, and T3, the proportions of SLN metastasis positivity were 21.3%, 35.3%, and 51.2%, respectively. In certain cases of T1 with 2 mm < DOI ≤ 5 mm and 8 mm < LD ≤ 20 mm, the proportion of SLN metastasis positivity was 40.9%. Conclusions: SLNB-navigated or assisted neck dissection can be added as an effective procedure for N0 neck control.

KW - indication

KW - neck dissection

KW - node-negative

KW - oral cavity cancer

KW - sentinel lymph node biopsy

UR - https://www.scopus.com/pages/publications/85166960679

UR - https://www.scopus.com/pages/publications/85166960679#tab=citedBy

U2 - 10.1002/hed.27477

DO - 10.1002/hed.27477

M3 - Article

C2 - 37552157

AN - SCOPUS:85166960679

SN - 1043-3074

VL - 45

SP - 2533

EP - 2543

JO - Head and Neck

JF - Head and Neck

IS - 10

ER -

Indications for sentinel lymph node biopsy in node-negative oral cancers

Abstract

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All Science Journal Classification (ASJC) codes

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