Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

Mingming Zhao; Atsutoshi Tazumi; Satoru Takayama; Nana Takenaka-Ninagawa; Minas Nalbandian; Miki Nagai; Yumi Nakamura; Masanori Nakasa; Akira Watanabe; Makoto Ikeya; Akitsu Hotta; Yuta Ito; Takahiko Sato; Hidetoshi Sakurai

doi:10.1016/j.stemcr.2020.06.004

Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

Mingming Zhao, Atsutoshi Tazumi, Satoru Takayama, Nana Takenaka-Ninagawa, Minas Nalbandian, Miki Nagai, Yumi Nakamura, Masanori Nakasa, Akira Watanabe, Makoto Ikeya, Akitsu Hotta, Yuta Ito, Takahiko Sato, Hidetoshi Sakurai

International Center for Cell and Gene Therapy

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Zhao et al. demonstrate that skeletal muscle progenitors and fetal muscle stem cells are time-dependently generated from hiPSCs in early and later stages of differentiation. The fetal muscle stem cells show better muscle regeneration potential and muscle function recovery in a mouse model of muscular dystrophy.

Original language	English
Pages (from-to)	80-94
Number of pages	15
Journal	Stem Cell Reports
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.stemcr.2020.06.004
Publication status	Published - 14-07-2020

All Science Journal Classification (ASJC) codes

Biochemistry
Genetics
Developmental Biology
Cell Biology

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10.1016/j.stemcr.2020.06.004

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Zhao, M., Tazumi, A., Takayama, S., Takenaka-Ninagawa, N., Nalbandian, M., Nagai, M., Nakamura, Y., Nakasa, M., Watanabe, A., Ikeya, M., Hotta, A., Ito, Y., Sato, T., & Sakurai, H. (2020). Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model. Stem Cell Reports, 15(1), 80-94. https://doi.org/10.1016/j.stemcr.2020.06.004

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abstract = "Zhao et al. demonstrate that skeletal muscle progenitors and fetal muscle stem cells are time-dependently generated from hiPSCs in early and later stages of differentiation. The fetal muscle stem cells show better muscle regeneration potential and muscle function recovery in a mouse model of muscular dystrophy.",

author = "Mingming Zhao and Atsutoshi Tazumi and Satoru Takayama and Nana Takenaka-Ninagawa and Minas Nalbandian and Miki Nagai and Yumi Nakamura and Masanori Nakasa and Akira Watanabe and Makoto Ikeya and Akitsu Hotta and Yuta Ito and Takahiko Sato and Hidetoshi Sakurai",

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Zhao, M, Tazumi, A, Takayama, S, Takenaka-Ninagawa, N, Nalbandian, M, Nagai, M, Nakamura, Y, Nakasa, M, Watanabe, A, Ikeya, M, Hotta, A, Ito, Y, Sato, T & Sakurai, H 2020, 'Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model', Stem Cell Reports, vol. 15, no. 1, pp. 80-94. https://doi.org/10.1016/j.stemcr.2020.06.004

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T1 - Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

AU - Zhao, Mingming

AU - Tazumi, Atsutoshi

AU - Takayama, Satoru

AU - Takenaka-Ninagawa, Nana

AU - Nalbandian, Minas

AU - Nagai, Miki

AU - Nakamura, Yumi

AU - Nakasa, Masanori

AU - Watanabe, Akira

AU - Ikeya, Makoto

AU - Hotta, Akitsu

AU - Ito, Yuta

AU - Sato, Takahiko

AU - Sakurai, Hidetoshi

PY - 2020/7/14

Y1 - 2020/7/14

N2 - Zhao et al. demonstrate that skeletal muscle progenitors and fetal muscle stem cells are time-dependently generated from hiPSCs in early and later stages of differentiation. The fetal muscle stem cells show better muscle regeneration potential and muscle function recovery in a mouse model of muscular dystrophy.

AB - Zhao et al. demonstrate that skeletal muscle progenitors and fetal muscle stem cells are time-dependently generated from hiPSCs in early and later stages of differentiation. The fetal muscle stem cells show better muscle regeneration potential and muscle function recovery in a mouse model of muscular dystrophy.

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Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

Abstract

All Science Journal Classification (ASJC) codes

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