Infective endocarditis with a huge mitral vegetation related to atopic dermatitis and high serum level of infection-related antiphospholipid antibody: A case report

Masahide Harada, Yutaro Nishi, Shinjiro Tamura, Yutaka Iba, Kohei Abe, Yuzuru Yanbe, Takehide Akimoto, Nobuhiro Takao, Sunao Watanabe, Noriaki Hayashida, Hitoshi Koyanagi

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

A 24-year-old woman with atopic dermatitis was admitted to our hospital with fever. Echocardiography showed a huge vegetation attached to the posterior mitral commissure without mitral valve dysfunction. Blood culture identified methicillin-sensitive Staphylococcus aureus. The serum level of antiphospholipid antibody was elevated. A splenic infarction occurred on the second hospital day. Surgery to resect the residual mobile vegetation was performed uneventfully on the 6th hospital day. The postoperative course was uneventful, and the patient was discharged after 4 weeks of antibiotic therapy. Preservation of the mitral valve is rare in the face of virulent Staphylococcus infection and the presence of a huge mobile vegetation. These findings were apparently related to the high serum level of infection-related antiphospholipid antibody and atopic dermatitis.

Original languageEnglish
Pages (from-to)135-140
Number of pages6
JournalJournal of cardiology
Volume42
Issue number3
Publication statusPublished - 01-09-2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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