Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease: A case report

Genya Nishikawa, Kogenta Nakamura, Yoshiaki Yamada, Takahiko Yoshizawa, Yoshiharu Kato, Remi Katsuda, Kenji Zennami, Motoi Tobiume, Shigeyuki Aoki, Tomohiro Taki, Nobuaki Honda

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Introduction. It has been reported that immunoglobulin G4-related systemic disease can spread to nearly every organ, and often presents as an inflammatory mass or masses at those sites. In the kidney, this disease is often diagnosed after a radical or partial nephrectomy following the discovery of an inflammatory mass which is often suspected to be a malignant tumor. Here, we present a rare case of inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease, which were diagnosed by computed tomography-guided biopsies. Case presentation. A 54-year-old Japanese man was referred to our hospital with suspected bilateral renal cancer, multiple lung metastases and autoimmune pancreatitis. His serum immunoglobulin G4 level was high. We used computed tomography-guided biopsies and histopathological examinations of the biopsied specimens to diagnose the tumors as immunoglobulin G4-related bilateral renal and lung inflammatory pseudotumors. Our patient was treated with oral prednisolone, and after one month of treatment, contrast-enhanced computed tomography demonstrated a general improvement, as noted by a reduction in size of the masses. Conclusion: Renal masses that are formed due to immunoglobulin G4-related disease require comprehensive diagnosis to prevent unnecessary surgical resections from being performed. Further consideration should be paid to immunoglobulin G4-related diseases in the future.

Original languageEnglish
Article number480
JournalJournal of Medical Case Reports
Volume5
DOIs
Publication statusPublished - 03-10-2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Dive into the research topics of 'Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease: A case report'. Together they form a unique fingerprint.

Cite this