A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited ≥90% of the H. pylori motility at a concentration of 500 μg/ml and the IC50 value was 50 μg/ml.
All Science Journal Classification (ASJC) codes
- Pharmaceutical Science