Inhibition of Helicobacter pylori motility by (+)-syringaresinol from unripe Japanese apricot

Mitsuo Miyazawa, Hirotoshi Utsunomiya, Ken Ichi Inada, Tomoki Yamada, Yoshiharu Okuno, Harunari Tanaka, Masae Tatematsu

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37 Citations (Scopus)

Abstract

A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited ≥90% of the H. pylori motility at a concentration of 500 μg/ml and the IC50 value was 50 μg/ml.

Original languageEnglish
Pages (from-to)172-173
Number of pages2
JournalBiological and Pharmaceutical Bulletin
Volume29
Issue number1
DOIs
Publication statusPublished - 01-01-2006

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science

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  • Cite this

    Miyazawa, M., Utsunomiya, H., Inada, K. I., Yamada, T., Okuno, Y., Tanaka, H., & Tatematsu, M. (2006). Inhibition of Helicobacter pylori motility by (+)-syringaresinol from unripe Japanese apricot. Biological and Pharmaceutical Bulletin, 29(1), 172-173. https://doi.org/10.1248/bpb.29.172