Intraoperative near-infrared indocyanine green-videoangiography (ICG-VA) and graphic analysis of fluorescence intensity in cerebral aneurysm surgery

Jumpei Oda, Yoko Kato, S. F. Chen, Paresh Sodhiya, T. Watabe, S. Imizu, D. Oguri, H. Sano, Yuichi Hirose

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

We present our preliminary experience with intraoperative near-infrared indocyanine green-videoangiography (ICG-VA) and analysis of blood flow dynamics using fluorescence intensity assessment in cerebral aneurysm clipping surgery. Thirty-nine patients with 43 intracranial aneurysms underwent microsurgical clipping. Intraoperative ICG-VA was performed before and after clip application. An infrared fluorescence module integrated into a surgical microscope was used to visualize fluorescence in the surgical field and we recorded the emitted fluorescent light. An integrated analytical visualization tool simultaneously analyzed the video sequence and converted it into an intensity diagram, which allowed an objective evaluation of the results rather than the subjective assessment of fluorescence using ICG-VA. Overall, ICG-VA was performed 137 times. Incomplete clipping was detected in four patients, which allowed suitable adjustment to completely obliterate the aneurysm. In 12 patients, perforators arising close to, or from, the aneurysmal neck were identified in the surgical field. In three patients, the ICG-VA intensity diagram provided valuable information leading to modification of the primary surgical maneuver. ICG-VA provides high resolution images allowing real-time assessment of the blood flow in the parent artery and arterial branches, including the perforators. The intensity diagram is useful for providing a more objective record of the hemodynamics than the traditional ICG-VA, which relies more on subjective assessment and may allow interobserver variability. We conclude that ICG-VA, combined with the intensity diagram, can reduce the morbidity and complications associated with aneurysm clipping and improve patient outcomes.

Original languageEnglish
Pages (from-to)1097-1100
Number of pages4
JournalJournal of Clinical Neuroscience
Volume18
Issue number8
DOIs
Publication statusPublished - 01-08-2011

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Indocyanine Green
Intracranial Aneurysm
Fluorescence
Aneurysm
Observer Variation
Surgical Instruments
Arteries
Hemodynamics
Morbidity
Light

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Oda, Jumpei ; Kato, Yoko ; Chen, S. F. ; Sodhiya, Paresh ; Watabe, T. ; Imizu, S. ; Oguri, D. ; Sano, H. ; Hirose, Yuichi. / Intraoperative near-infrared indocyanine green-videoangiography (ICG-VA) and graphic analysis of fluorescence intensity in cerebral aneurysm surgery. In: Journal of Clinical Neuroscience. 2011 ; Vol. 18, No. 8. pp. 1097-1100.
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Intraoperative near-infrared indocyanine green-videoangiography (ICG-VA) and graphic analysis of fluorescence intensity in cerebral aneurysm surgery. / Oda, Jumpei; Kato, Yoko; Chen, S. F.; Sodhiya, Paresh; Watabe, T.; Imizu, S.; Oguri, D.; Sano, H.; Hirose, Yuichi.

In: Journal of Clinical Neuroscience, Vol. 18, No. 8, 01.08.2011, p. 1097-1100.

Research output: Contribution to journalArticle

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AU - Oda, Jumpei

AU - Kato, Yoko

AU - Chen, S. F.

AU - Sodhiya, Paresh

AU - Watabe, T.

AU - Imizu, S.

AU - Oguri, D.

AU - Sano, H.

AU - Hirose, Yuichi

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AB - We present our preliminary experience with intraoperative near-infrared indocyanine green-videoangiography (ICG-VA) and analysis of blood flow dynamics using fluorescence intensity assessment in cerebral aneurysm clipping surgery. Thirty-nine patients with 43 intracranial aneurysms underwent microsurgical clipping. Intraoperative ICG-VA was performed before and after clip application. An infrared fluorescence module integrated into a surgical microscope was used to visualize fluorescence in the surgical field and we recorded the emitted fluorescent light. An integrated analytical visualization tool simultaneously analyzed the video sequence and converted it into an intensity diagram, which allowed an objective evaluation of the results rather than the subjective assessment of fluorescence using ICG-VA. Overall, ICG-VA was performed 137 times. Incomplete clipping was detected in four patients, which allowed suitable adjustment to completely obliterate the aneurysm. In 12 patients, perforators arising close to, or from, the aneurysmal neck were identified in the surgical field. In three patients, the ICG-VA intensity diagram provided valuable information leading to modification of the primary surgical maneuver. ICG-VA provides high resolution images allowing real-time assessment of the blood flow in the parent artery and arterial branches, including the perforators. The intensity diagram is useful for providing a more objective record of the hemodynamics than the traditional ICG-VA, which relies more on subjective assessment and may allow interobserver variability. We conclude that ICG-VA, combined with the intensity diagram, can reduce the morbidity and complications associated with aneurysm clipping and improve patient outcomes.

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