Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population

Fumihito Sato; Isao Oze; Daisuke Kawakita; Noriyuki Yamamoto; Hidemi Ito; Satoyo Hosono; Takeshi Suzuki; Takakazu Kawase; Hiroki Furue; Miki Watanabe; Shunzo Hatooka; Yasushi Yatabe; Yasuhisa Hasegawa; Masayuki Shinoda; Minoru Ueda; Kazuo Tajima; Hideo Tanaka; Keitaro Matsuo

doi:10.1002/hed.21649

Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population

Fumihito Sato, Isao Oze, Daisuke Kawakita, Noriyuki Yamamoto, Hidemi Ito, Satoyo Hosono, Takeshi Suzuki, Takakazu Kawase, Hiroki Furue, Miki Watanabe, Shunzo Hatooka, Yasushi Yatabe, Yasuhisa Hasegawa, Masayuki Shinoda, Minoru Ueda, Kazuo Tajima, Hideo Tanaka, Keitaro Matsuo

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

Background Oral hygiene is attracting increasing attention as a potential risk factor for cancers. To investigate the association between toothbrushing frequency and upper aerodigestive tract (UADT) cancer, the authors conducted a large-scale case-control study. Methods A total of 856 UADT cancer case participants and 2696 age- and sex-matched control subjects without cancer were included. Edentulous or participants with unknown frequency of toothbrushing or number of remaining teeth were excluded. Associations were assessed by odds ratios and 95% confidence intervals in logistic regression models with adjustment for potential confounders. Results Compared with toothbrushing once per day, the adjusted odds ratio for brushing twice or more was 0.82 (95% confidence interval: 0.68, 0.99) whereas that for not brushing was 1.79 (0.79, 4.05). This association was observed especially in subjects who had a history of heavy smoking or drinking. Conclusions The authors suggest that toothbrushing could have a protective effect for UADT cancer.

Original language	English
Pages (from-to)	1628-1637
Number of pages	10
Journal	Head and Neck
Volume	33
Issue number	11
DOIs	https://doi.org/10.1002/hed.21649
Publication status	Published - 11-2011
Externally published	Yes

All Science Journal Classification (ASJC) codes

Otorhinolaryngology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/hed.21649

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Sato, F., Oze, I., Kawakita, D., Yamamoto, N., Ito, H., Hosono, S., Suzuki, T., Kawase, T., Furue, H., Watanabe, M., Hatooka, S., Yatabe, Y., Hasegawa, Y., Shinoda, M., Ueda, M., Tajima, K., Tanaka, H., & Matsuo, K. (2011). Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population. Head and Neck, 33(11), 1628-1637. https://doi.org/10.1002/hed.21649

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title = "Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population",

abstract = "Background Oral hygiene is attracting increasing attention as a potential risk factor for cancers. To investigate the association between toothbrushing frequency and upper aerodigestive tract (UADT) cancer, the authors conducted a large-scale case-control study. Methods A total of 856 UADT cancer case participants and 2696 age- and sex-matched control subjects without cancer were included. Edentulous or participants with unknown frequency of toothbrushing or number of remaining teeth were excluded. Associations were assessed by odds ratios and 95% confidence intervals in logistic regression models with adjustment for potential confounders. Results Compared with toothbrushing once per day, the adjusted odds ratio for brushing twice or more was 0.82 (95% confidence interval: 0.68, 0.99) whereas that for not brushing was 1.79 (0.79, 4.05). This association was observed especially in subjects who had a history of heavy smoking or drinking. Conclusions The authors suggest that toothbrushing could have a protective effect for UADT cancer.",

author = "Fumihito Sato and Isao Oze and Daisuke Kawakita and Noriyuki Yamamoto and Hidemi Ito and Satoyo Hosono and Takeshi Suzuki and Takakazu Kawase and Hiroki Furue and Miki Watanabe and Shunzo Hatooka and Yasushi Yatabe and Yasuhisa Hasegawa and Masayuki Shinoda and Minoru Ueda and Kazuo Tajima and Hideo Tanaka and Keitaro Matsuo",

year = "2011",

month = nov,

doi = "10.1002/hed.21649",

language = "English",

volume = "33",

pages = "1628--1637",

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Sato, F, Oze, I, Kawakita, D, Yamamoto, N, Ito, H, Hosono, S, Suzuki, T, Kawase, T, Furue, H, Watanabe, M, Hatooka, S, Yatabe, Y, Hasegawa, Y, Shinoda, M, Ueda, M, Tajima, K, Tanaka, H & Matsuo, K 2011, 'Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population', Head and Neck, vol. 33, no. 11, pp. 1628-1637. https://doi.org/10.1002/hed.21649

TY - JOUR

T1 - Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population

AU - Sato, Fumihito

AU - Oze, Isao

AU - Kawakita, Daisuke

AU - Yamamoto, Noriyuki

AU - Ito, Hidemi

AU - Hosono, Satoyo

AU - Suzuki, Takeshi

AU - Kawase, Takakazu

AU - Furue, Hiroki

AU - Watanabe, Miki

AU - Hatooka, Shunzo

AU - Yatabe, Yasushi

AU - Hasegawa, Yasuhisa

AU - Shinoda, Masayuki

AU - Ueda, Minoru

AU - Tajima, Kazuo

AU - Tanaka, Hideo

AU - Matsuo, Keitaro

PY - 2011/11

Y1 - 2011/11

N2 - Background Oral hygiene is attracting increasing attention as a potential risk factor for cancers. To investigate the association between toothbrushing frequency and upper aerodigestive tract (UADT) cancer, the authors conducted a large-scale case-control study. Methods A total of 856 UADT cancer case participants and 2696 age- and sex-matched control subjects without cancer were included. Edentulous or participants with unknown frequency of toothbrushing or number of remaining teeth were excluded. Associations were assessed by odds ratios and 95% confidence intervals in logistic regression models with adjustment for potential confounders. Results Compared with toothbrushing once per day, the adjusted odds ratio for brushing twice or more was 0.82 (95% confidence interval: 0.68, 0.99) whereas that for not brushing was 1.79 (0.79, 4.05). This association was observed especially in subjects who had a history of heavy smoking or drinking. Conclusions The authors suggest that toothbrushing could have a protective effect for UADT cancer.

AB - Background Oral hygiene is attracting increasing attention as a potential risk factor for cancers. To investigate the association between toothbrushing frequency and upper aerodigestive tract (UADT) cancer, the authors conducted a large-scale case-control study. Methods A total of 856 UADT cancer case participants and 2696 age- and sex-matched control subjects without cancer were included. Edentulous or participants with unknown frequency of toothbrushing or number of remaining teeth were excluded. Associations were assessed by odds ratios and 95% confidence intervals in logistic regression models with adjustment for potential confounders. Results Compared with toothbrushing once per day, the adjusted odds ratio for brushing twice or more was 0.82 (95% confidence interval: 0.68, 0.99) whereas that for not brushing was 1.79 (0.79, 4.05). This association was observed especially in subjects who had a history of heavy smoking or drinking. Conclusions The authors suggest that toothbrushing could have a protective effect for UADT cancer.

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JO - Head and Neck

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IS - 11

ER -

Inverse association between toothbrushing and upper aerodigestive tract cancer risk in a Japanese population

Abstract

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