TY - JOUR
T1 - Investigation of nasal meticillin-resistant Staphylococcus aureus carriage in a haemodialysis clinic in Japan
AU - Uehara, Y.
AU - Kuwahara-Arai, K.
AU - Hori, S.
AU - Kikuchi, K.
AU - Yanai, M.
AU - Hiramatsu, K.
N1 - Funding Information:
This work was supported by a Grant-in-Aid (S0991013) from Ministry of Education, Culture, Sport, Science, and Technology (MEXT), Japan for the Foundation of Strategic Research Projects in Private Universities, President's Special Project Research Grant-in-Aid in Juntendo University (2009), and Nihon University School of Medicine Alumni Association 60th Anniversary Fund Research Grant (2011).
PY - 2013/5
Y1 - 2013/5
N2 - Patients and healthcare workers in a Japanese haemodialysis clinic were investigated for nasal carriage of meticillin-resistant Staphylococcus aureus (MRSA). MRSA carriage was found in 10 (8.9%) of 112 patients in the first year and four (3.9%) of 103 patients in the second year. All isolated MRSA samples carried staphylococcal cassette chromosome mec type II or III and classified as clonal complex 5, which were common as healthcare-associated strains. Pulsed-field gel electrophoresis indicated horizontal transmission limited to two pairs of patients in one session. One of 54 healthcare workers carried MRSA genetically unrelated to patients' strains. Infection control measures based on the US Centers for Disease Control and Prevention's recommendation showed limited spread of MRSA in a haemodialysis room.
AB - Patients and healthcare workers in a Japanese haemodialysis clinic were investigated for nasal carriage of meticillin-resistant Staphylococcus aureus (MRSA). MRSA carriage was found in 10 (8.9%) of 112 patients in the first year and four (3.9%) of 103 patients in the second year. All isolated MRSA samples carried staphylococcal cassette chromosome mec type II or III and classified as clonal complex 5, which were common as healthcare-associated strains. Pulsed-field gel electrophoresis indicated horizontal transmission limited to two pairs of patients in one session. One of 54 healthcare workers carried MRSA genetically unrelated to patients' strains. Infection control measures based on the US Centers for Disease Control and Prevention's recommendation showed limited spread of MRSA in a haemodialysis room.
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U2 - 10.1016/j.jhin.2013.01.004
DO - 10.1016/j.jhin.2013.01.004
M3 - Article
C2 - 23419596
AN - SCOPUS:84876312779
VL - 84
SP - 81
EP - 84
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
SN - 0195-6701
IS - 1
ER -