IQ·SPECT technology and its clinical applications using multicenter normal databases

Kenichi Nakajima, Koichi Okuda, Mitsuru Momose, Shinro Matsuo, Chisato Kondo, Masayoshi Sarai, Takayuki Shibutani, Masahisa Onoguchi, Takeshi Shimizu, A. Hans Vija

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

IQ·SPECT (Siemens Medical Solutions) is a solution for high-sensitivity and short-time acquisition imaging of the heart for a variable angle general purpose gamma camera. It consists of a multi-focal collimator, a cardio-centric orbit and advanced iterative reconstruction, modeling the image formation physics accurately. The multi-focal collimator enables distance-dependent enlargement of the center region while avoiding truncation at the edges. With the specified configuration and a cardio-centric orbit it can obtain a fourfold sensitivity increase for the heart at the center of the scan orbit. Since IQ·SPECT shows characteristic distribution patterns in the myocardium, appropriate acquisition and processing conditions are required, and normal databases are convenient for quantification of both normal and abnormal perfusion images. The use of prone imaging can be a good option when X-ray computed tomography (CT) is not available for attenuation correction. CT-based attenuation correction changes count distribution significantly in the inferior wall and around the apex, hence image interpretation training and additional use of normal databases are recommended. Recent reports regarding its technology, Japanese Society of Nuclear Medicine working group activities, and clinical studies using 201Tl and 99mTc-perfusion tracers in Japan are summarized.

Original languageEnglish
Pages (from-to)649-659
Number of pages11
JournalAnnals of Nuclear Medicine
Volume31
Issue number9
DOIs
Publication statusPublished - 01-11-2017

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Orbit
Databases
Technology
Perfusion
Gamma Cameras
X Ray Computed Tomography
Computer-Assisted Image Processing
Physics
Myocardium
Japan
Tomography

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Nakajima, Kenichi ; Okuda, Koichi ; Momose, Mitsuru ; Matsuo, Shinro ; Kondo, Chisato ; Sarai, Masayoshi ; Shibutani, Takayuki ; Onoguchi, Masahisa ; Shimizu, Takeshi ; Vija, A. Hans. / IQ·SPECT technology and its clinical applications using multicenter normal databases. In: Annals of Nuclear Medicine. 2017 ; Vol. 31, No. 9. pp. 649-659.
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Nakajima, K, Okuda, K, Momose, M, Matsuo, S, Kondo, C, Sarai, M, Shibutani, T, Onoguchi, M, Shimizu, T & Vija, AH 2017, 'IQ·SPECT technology and its clinical applications using multicenter normal databases', Annals of Nuclear Medicine, vol. 31, no. 9, pp. 649-659. https://doi.org/10.1007/s12149-017-1210-3

IQ·SPECT technology and its clinical applications using multicenter normal databases. / Nakajima, Kenichi; Okuda, Koichi; Momose, Mitsuru; Matsuo, Shinro; Kondo, Chisato; Sarai, Masayoshi; Shibutani, Takayuki; Onoguchi, Masahisa; Shimizu, Takeshi; Vija, A. Hans.

In: Annals of Nuclear Medicine, Vol. 31, No. 9, 01.11.2017, p. 649-659.

Research output: Contribution to journalReview article

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AU - Nakajima, Kenichi

AU - Okuda, Koichi

AU - Momose, Mitsuru

AU - Matsuo, Shinro

AU - Kondo, Chisato

AU - Sarai, Masayoshi

AU - Shibutani, Takayuki

AU - Onoguchi, Masahisa

AU - Shimizu, Takeshi

AU - Vija, A. Hans

PY - 2017/11/1

Y1 - 2017/11/1

N2 - IQ·SPECT (Siemens Medical Solutions) is a solution for high-sensitivity and short-time acquisition imaging of the heart for a variable angle general purpose gamma camera. It consists of a multi-focal collimator, a cardio-centric orbit and advanced iterative reconstruction, modeling the image formation physics accurately. The multi-focal collimator enables distance-dependent enlargement of the center region while avoiding truncation at the edges. With the specified configuration and a cardio-centric orbit it can obtain a fourfold sensitivity increase for the heart at the center of the scan orbit. Since IQ·SPECT shows characteristic distribution patterns in the myocardium, appropriate acquisition and processing conditions are required, and normal databases are convenient for quantification of both normal and abnormal perfusion images. The use of prone imaging can be a good option when X-ray computed tomography (CT) is not available for attenuation correction. CT-based attenuation correction changes count distribution significantly in the inferior wall and around the apex, hence image interpretation training and additional use of normal databases are recommended. Recent reports regarding its technology, Japanese Society of Nuclear Medicine working group activities, and clinical studies using 201Tl and 99mTc-perfusion tracers in Japan are summarized.

AB - IQ·SPECT (Siemens Medical Solutions) is a solution for high-sensitivity and short-time acquisition imaging of the heart for a variable angle general purpose gamma camera. It consists of a multi-focal collimator, a cardio-centric orbit and advanced iterative reconstruction, modeling the image formation physics accurately. The multi-focal collimator enables distance-dependent enlargement of the center region while avoiding truncation at the edges. With the specified configuration and a cardio-centric orbit it can obtain a fourfold sensitivity increase for the heart at the center of the scan orbit. Since IQ·SPECT shows characteristic distribution patterns in the myocardium, appropriate acquisition and processing conditions are required, and normal databases are convenient for quantification of both normal and abnormal perfusion images. The use of prone imaging can be a good option when X-ray computed tomography (CT) is not available for attenuation correction. CT-based attenuation correction changes count distribution significantly in the inferior wall and around the apex, hence image interpretation training and additional use of normal databases are recommended. Recent reports regarding its technology, Japanese Society of Nuclear Medicine working group activities, and clinical studies using 201Tl and 99mTc-perfusion tracers in Japan are summarized.

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