Is laser conization adequate for therapeutic excision of adenocarcinoma in situ of the uterine cervix?

Yasuo Akiba, Kaneyuki Kubushiro, Takeshi Fukuchi, Takuma Fujii, Katsumi Tsukazaki, Makio Mukai, Shiro Nozawa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Aims: To determine the safety of uterine-preserving operations for adenocarcinoma in situ of the cervix. Methods: Fifteen cases of adenocarcinoma in situ (AIS) were diagnosed using neodymium:yttrium aluminum garnet (Nd:YAG) laser conization. The accuracy of preconization histology or cytology was evaluated in 15 AIS cases. In these AIS cases, we investigated how far the tumor was located from the squamocolumnar junction (SCJ) and the endocervix. Fourteen cases of the 15 AIS-affected patients were treated using laser conization alone. These patients were closely followed up. Results: Precise agreement between preconization diagnosis and conization histology was seen in 46.7% (7/ 15) of the AIS cases. In 14 of the 15 cases of AIS (93.3%), the tumor was adjacent to the transitional zone, within 3 mm of the SCJ, and in the other case (6.7%), the tumor was between 0 and 5 mm away from the SCJ. In all subjects, cone height was 8-18 mm (mean 13.1 mm). None of the 15 patients showed any recurrence of AIS during follow up ranging from 15 to 75 months (43.1 months on average). Conclusions: Women with AIS who want to preserve their fecundity might be treated with laser conization alone.

Original languageEnglish
Pages (from-to)252-256
Number of pages5
JournalJournal of Obstetrics and Gynaecology Research
Volume31
Issue number3
DOIs
Publication statusPublished - 01-06-2005
Externally publishedYes

Fingerprint

Conization
Cervix Uteri
Lasers
Therapeutics
Histology
Neodymium
Adenocarcinoma in Situ
Neoplasms
Solid-State Lasers
Fertility
Cell Biology
Safety
Recurrence

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Cite this

Akiba, Yasuo ; Kubushiro, Kaneyuki ; Fukuchi, Takeshi ; Fujii, Takuma ; Tsukazaki, Katsumi ; Mukai, Makio ; Nozawa, Shiro. / Is laser conization adequate for therapeutic excision of adenocarcinoma in situ of the uterine cervix?. In: Journal of Obstetrics and Gynaecology Research. 2005 ; Vol. 31, No. 3. pp. 252-256.
@article{fd90e70077d046a8b0a2299540d07d96,
title = "Is laser conization adequate for therapeutic excision of adenocarcinoma in situ of the uterine cervix?",
abstract = "Aims: To determine the safety of uterine-preserving operations for adenocarcinoma in situ of the cervix. Methods: Fifteen cases of adenocarcinoma in situ (AIS) were diagnosed using neodymium:yttrium aluminum garnet (Nd:YAG) laser conization. The accuracy of preconization histology or cytology was evaluated in 15 AIS cases. In these AIS cases, we investigated how far the tumor was located from the squamocolumnar junction (SCJ) and the endocervix. Fourteen cases of the 15 AIS-affected patients were treated using laser conization alone. These patients were closely followed up. Results: Precise agreement between preconization diagnosis and conization histology was seen in 46.7{\%} (7/ 15) of the AIS cases. In 14 of the 15 cases of AIS (93.3{\%}), the tumor was adjacent to the transitional zone, within 3 mm of the SCJ, and in the other case (6.7{\%}), the tumor was between 0 and 5 mm away from the SCJ. In all subjects, cone height was 8-18 mm (mean 13.1 mm). None of the 15 patients showed any recurrence of AIS during follow up ranging from 15 to 75 months (43.1 months on average). Conclusions: Women with AIS who want to preserve their fecundity might be treated with laser conization alone.",
author = "Yasuo Akiba and Kaneyuki Kubushiro and Takeshi Fukuchi and Takuma Fujii and Katsumi Tsukazaki and Makio Mukai and Shiro Nozawa",
year = "2005",
month = "6",
day = "1",
doi = "10.1111/j.1447-0756.2005.00279.x",
language = "English",
volume = "31",
pages = "252--256",
journal = "Journal of Obstetrics and Gynaecology Research",
issn = "1341-8076",
publisher = "Blackwell Publishing Asia",
number = "3",

}

Is laser conization adequate for therapeutic excision of adenocarcinoma in situ of the uterine cervix? / Akiba, Yasuo; Kubushiro, Kaneyuki; Fukuchi, Takeshi; Fujii, Takuma; Tsukazaki, Katsumi; Mukai, Makio; Nozawa, Shiro.

In: Journal of Obstetrics and Gynaecology Research, Vol. 31, No. 3, 01.06.2005, p. 252-256.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Is laser conization adequate for therapeutic excision of adenocarcinoma in situ of the uterine cervix?

AU - Akiba, Yasuo

AU - Kubushiro, Kaneyuki

AU - Fukuchi, Takeshi

AU - Fujii, Takuma

AU - Tsukazaki, Katsumi

AU - Mukai, Makio

AU - Nozawa, Shiro

PY - 2005/6/1

Y1 - 2005/6/1

N2 - Aims: To determine the safety of uterine-preserving operations for adenocarcinoma in situ of the cervix. Methods: Fifteen cases of adenocarcinoma in situ (AIS) were diagnosed using neodymium:yttrium aluminum garnet (Nd:YAG) laser conization. The accuracy of preconization histology or cytology was evaluated in 15 AIS cases. In these AIS cases, we investigated how far the tumor was located from the squamocolumnar junction (SCJ) and the endocervix. Fourteen cases of the 15 AIS-affected patients were treated using laser conization alone. These patients were closely followed up. Results: Precise agreement between preconization diagnosis and conization histology was seen in 46.7% (7/ 15) of the AIS cases. In 14 of the 15 cases of AIS (93.3%), the tumor was adjacent to the transitional zone, within 3 mm of the SCJ, and in the other case (6.7%), the tumor was between 0 and 5 mm away from the SCJ. In all subjects, cone height was 8-18 mm (mean 13.1 mm). None of the 15 patients showed any recurrence of AIS during follow up ranging from 15 to 75 months (43.1 months on average). Conclusions: Women with AIS who want to preserve their fecundity might be treated with laser conization alone.

AB - Aims: To determine the safety of uterine-preserving operations for adenocarcinoma in situ of the cervix. Methods: Fifteen cases of adenocarcinoma in situ (AIS) were diagnosed using neodymium:yttrium aluminum garnet (Nd:YAG) laser conization. The accuracy of preconization histology or cytology was evaluated in 15 AIS cases. In these AIS cases, we investigated how far the tumor was located from the squamocolumnar junction (SCJ) and the endocervix. Fourteen cases of the 15 AIS-affected patients were treated using laser conization alone. These patients were closely followed up. Results: Precise agreement between preconization diagnosis and conization histology was seen in 46.7% (7/ 15) of the AIS cases. In 14 of the 15 cases of AIS (93.3%), the tumor was adjacent to the transitional zone, within 3 mm of the SCJ, and in the other case (6.7%), the tumor was between 0 and 5 mm away from the SCJ. In all subjects, cone height was 8-18 mm (mean 13.1 mm). None of the 15 patients showed any recurrence of AIS during follow up ranging from 15 to 75 months (43.1 months on average). Conclusions: Women with AIS who want to preserve their fecundity might be treated with laser conization alone.

UR - http://www.scopus.com/inward/record.url?scp=21744449144&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21744449144&partnerID=8YFLogxK

U2 - 10.1111/j.1447-0756.2005.00279.x

DO - 10.1111/j.1447-0756.2005.00279.x

M3 - Article

VL - 31

SP - 252

EP - 256

JO - Journal of Obstetrics and Gynaecology Research

JF - Journal of Obstetrics and Gynaecology Research

SN - 1341-8076

IS - 3

ER -