Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma

T. Nomura, M. Ohtsuki, S. Matsui, Chiho Ichinose, H. Nomura, Y. Hagino, K. Iwase, H. Ichinose, K. Fujita, T. Nagatsu

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Although the existence of three different cDNA forms of human GTP cyclohydrolase I (GCH I) have been reported (Togari et al., 1992), the full-length sequence of any human GCH I cDNA involving poly (A) tail has not yet been documented. In the present study, we first isolated a full-length cDNA clone encoding human GCH I type 1 from human pheochromocytoma cDNA library. The length of the cDNA insert was 2,921 base pairs including poly (A) tail. RNA blot analysis showed a single niRNA species of 4.0kb in human pheochromocytoma tissue.

Original languageEnglish
Pages (from-to)237-242
Number of pages6
JournalJournal of Neural Transmission
Volume101
Issue number1-3
DOIs
Publication statusPublished - 01-02-1995

Fingerprint

GTP Cyclohydrolase
Pheochromocytoma
Complementary DNA
Clone Cells
Messenger RNA
Gene Library
Base Pairing
RNA

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Nomura, T. ; Ohtsuki, M. ; Matsui, S. ; Ichinose, Chiho ; Nomura, H. ; Hagino, Y. ; Iwase, K. ; Ichinose, H. ; Fujita, K. ; Nagatsu, T. / Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma. In: Journal of Neural Transmission. 1995 ; Vol. 101, No. 1-3. pp. 237-242.
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Nomura, T, Ohtsuki, M, Matsui, S, Ichinose, C, Nomura, H, Hagino, Y, Iwase, K, Ichinose, H, Fujita, K & Nagatsu, T 1995, 'Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma', Journal of Neural Transmission, vol. 101, no. 1-3, pp. 237-242. https://doi.org/10.1007/BF01271561

Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma. / Nomura, T.; Ohtsuki, M.; Matsui, S.; Ichinose, Chiho; Nomura, H.; Hagino, Y.; Iwase, K.; Ichinose, H.; Fujita, K.; Nagatsu, T.

In: Journal of Neural Transmission, Vol. 101, No. 1-3, 01.02.1995, p. 237-242.

Research output: Contribution to journalArticle

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AU - Nomura, T.

AU - Ohtsuki, M.

AU - Matsui, S.

AU - Ichinose, Chiho

AU - Nomura, H.

AU - Hagino, Y.

AU - Iwase, K.

AU - Ichinose, H.

AU - Fujita, K.

AU - Nagatsu, T.

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