@article{c1d572299db94d50a45c6ae492d0b9cd,
title = "Isolation of a human monoclonal antibody with strong neutralizing activity against diphtheria toxin",
abstract = "We isolated a human monoclonal antibody against diphtheria toxin (DT). It bound to fragment B with a binding activity (Kd) of 3.01 nM. The neutralizing activity assayed by the rabbit skin test was estimated to be 73,600 IU/g. This could be used as a therapeutic drug against DT in place of the traditional equine sera.",
author = "Mai Kakita and Tsuyoshi Takahashi and Takako Komiya and Yoshitaka Iba and Takao Tsuji and Yoshikazu Kurosawa and Motohide Takahashi",
note = "Funding Information: The assistance of residents of the Tahuayo, Amazon, Ucayali, Putumayo, and Nanay Rivers is gratefully acknowledged. Special thanks go to colleagues and staff at IIAP-Iquitos, IIAP-Pucallpa, INIA-Iquitos, PNCC-Iquitos, PNCCPucallpa, INADE-Iquitos, INRENA-El Estrecho, and INPA-Manaus. Mario Pinedo, Jorge Soplin, Dennis Huayllahua and Pilar Diaz are acknowledged for their exceptional support and collaboration. Field research was generously funded by the Rainforest Conservation Fund (RCF) of Chicago, Illinois; the Dallas Zoological Society, and the Tropical Conservation and Development Program of the University of Florida.",
year = "2006",
month = jun,
doi = "10.1128/IAI.01731-05",
language = "English",
volume = "74",
pages = "3682--3683",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "6",
}