Japan renal biopsy registry: The first nationwide, web-based, and prospective registry system of renal biopsies in Japan

Hitoshi Sugiyama, Hitoshi Yokoyama, Hiroshi Sato, Takao Saito, Yukimasa Kohda, Shinichi Nishi, Kazuhiko Tsuruya, Hideyasu Kiyomoto, Hiroyuki Iida, Tamaki Sasaki, Makoto Higuchi, Motoshi Hattori, Kazumasa Oka, Shoji Kagami, Michio Nagata, Tetsuya Kawamura, Masataka Honda, Yuichiro Fukasawa, Atsushi Fukatsu, Kunio MorozumiNorishige Yoshikawa, Yukio Yuzawa, Seiichi Matsuo, Yutaka Kiyohara, Kensuke Joh, Takashi Taguchi, Hirofumi Makino

Research output: Contribution to journalReview article

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Abstract

Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.

Original languageEnglish
Pages (from-to)493-503
Number of pages11
JournalClinical and Experimental Nephrology
Volume15
Issue number4
DOIs
Publication statusPublished - 01-08-2011

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Registries
Japan
Kidney
Biopsy
Membranous Glomerulonephritis
IGA Glomerulonephritis
Transplants
Information Centers
Nephrology
Information Services
Nephrotic Syndrome
Kidney Transplantation
Cross-Sectional Studies
Demography
Databases

All Science Journal Classification (ASJC) codes

  • Physiology
  • Nephrology
  • Physiology (medical)

Cite this

Sugiyama, Hitoshi ; Yokoyama, Hitoshi ; Sato, Hiroshi ; Saito, Takao ; Kohda, Yukimasa ; Nishi, Shinichi ; Tsuruya, Kazuhiko ; Kiyomoto, Hideyasu ; Iida, Hiroyuki ; Sasaki, Tamaki ; Higuchi, Makoto ; Hattori, Motoshi ; Oka, Kazumasa ; Kagami, Shoji ; Nagata, Michio ; Kawamura, Tetsuya ; Honda, Masataka ; Fukasawa, Yuichiro ; Fukatsu, Atsushi ; Morozumi, Kunio ; Yoshikawa, Norishige ; Yuzawa, Yukio ; Matsuo, Seiichi ; Kiyohara, Yutaka ; Joh, Kensuke ; Taguchi, Takashi ; Makino, Hirofumi. / Japan renal biopsy registry : The first nationwide, web-based, and prospective registry system of renal biopsies in Japan. In: Clinical and Experimental Nephrology. 2011 ; Vol. 15, No. 4. pp. 493-503.
@article{c0403fbf2fd346879abf405969b020dd,
title = "Japan renal biopsy registry: The first nationwide, web-based, and prospective registry system of renal biopsies in Japan",
abstract = "Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8{\%}) and 92 renal grafts (11.2{\%}) in 2007, and 1400 native kidneys (88.5{\%}) and 182 renal grafts (11.5{\%}) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4{\%}), followed by nephrotic syndrome (16.8{\%}) and renal transplantation (11.2{\%}) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9{\%}) and 2008 (30.2{\%}). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4{\%}) and 2008 (25.7{\%}). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.",
author = "Hitoshi Sugiyama and Hitoshi Yokoyama and Hiroshi Sato and Takao Saito and Yukimasa Kohda and Shinichi Nishi and Kazuhiko Tsuruya and Hideyasu Kiyomoto and Hiroyuki Iida and Tamaki Sasaki and Makoto Higuchi and Motoshi Hattori and Kazumasa Oka and Shoji Kagami and Michio Nagata and Tetsuya Kawamura and Masataka Honda and Yuichiro Fukasawa and Atsushi Fukatsu and Kunio Morozumi and Norishige Yoshikawa and Yukio Yuzawa and Seiichi Matsuo and Yutaka Kiyohara and Kensuke Joh and Takashi Taguchi and Hirofumi Makino",
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month = "8",
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language = "English",
volume = "15",
pages = "493--503",
journal = "Clinical and Experimental Nephrology",
issn = "1342-1751",
publisher = "Springer Japan",
number = "4",

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Sugiyama, H, Yokoyama, H, Sato, H, Saito, T, Kohda, Y, Nishi, S, Tsuruya, K, Kiyomoto, H, Iida, H, Sasaki, T, Higuchi, M, Hattori, M, Oka, K, Kagami, S, Nagata, M, Kawamura, T, Honda, M, Fukasawa, Y, Fukatsu, A, Morozumi, K, Yoshikawa, N, Yuzawa, Y, Matsuo, S, Kiyohara, Y, Joh, K, Taguchi, T & Makino, H 2011, 'Japan renal biopsy registry: The first nationwide, web-based, and prospective registry system of renal biopsies in Japan', Clinical and Experimental Nephrology, vol. 15, no. 4, pp. 493-503. https://doi.org/10.1007/s10157-011-0430-4

Japan renal biopsy registry : The first nationwide, web-based, and prospective registry system of renal biopsies in Japan. / Sugiyama, Hitoshi; Yokoyama, Hitoshi; Sato, Hiroshi; Saito, Takao; Kohda, Yukimasa; Nishi, Shinichi; Tsuruya, Kazuhiko; Kiyomoto, Hideyasu; Iida, Hiroyuki; Sasaki, Tamaki; Higuchi, Makoto; Hattori, Motoshi; Oka, Kazumasa; Kagami, Shoji; Nagata, Michio; Kawamura, Tetsuya; Honda, Masataka; Fukasawa, Yuichiro; Fukatsu, Atsushi; Morozumi, Kunio; Yoshikawa, Norishige; Yuzawa, Yukio; Matsuo, Seiichi; Kiyohara, Yutaka; Joh, Kensuke; Taguchi, Takashi; Makino, Hirofumi.

In: Clinical and Experimental Nephrology, Vol. 15, No. 4, 01.08.2011, p. 493-503.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Japan renal biopsy registry

T2 - The first nationwide, web-based, and prospective registry system of renal biopsies in Japan

AU - Sugiyama, Hitoshi

AU - Yokoyama, Hitoshi

AU - Sato, Hiroshi

AU - Saito, Takao

AU - Kohda, Yukimasa

AU - Nishi, Shinichi

AU - Tsuruya, Kazuhiko

AU - Kiyomoto, Hideyasu

AU - Iida, Hiroyuki

AU - Sasaki, Tamaki

AU - Higuchi, Makoto

AU - Hattori, Motoshi

AU - Oka, Kazumasa

AU - Kagami, Shoji

AU - Nagata, Michio

AU - Kawamura, Tetsuya

AU - Honda, Masataka

AU - Fukasawa, Yuichiro

AU - Fukatsu, Atsushi

AU - Morozumi, Kunio

AU - Yoshikawa, Norishige

AU - Yuzawa, Yukio

AU - Matsuo, Seiichi

AU - Kiyohara, Yutaka

AU - Joh, Kensuke

AU - Taguchi, Takashi

AU - Makino, Hirofumi

PY - 2011/8/1

Y1 - 2011/8/1

N2 - Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.

AB - Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.

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