TY - JOUR
T1 - Japan renal biopsy registry
T2 - The first nationwide, web-based, and prospective registry system of renal biopsies in Japan
AU - Sugiyama, Hitoshi
AU - Yokoyama, Hitoshi
AU - Sato, Hiroshi
AU - Saito, Takao
AU - Kohda, Yukimasa
AU - Nishi, Shinichi
AU - Tsuruya, Kazuhiko
AU - Kiyomoto, Hideyasu
AU - Iida, Hiroyuki
AU - Sasaki, Tamaki
AU - higuchi, makoto
AU - Hattori, Motoshi
AU - Oka, Kazumasa
AU - Kagami, Shoji
AU - Nagata, Michio
AU - Kawamura, Tetsuya
AU - Honda, Masataka
AU - Fukasawa, Yuichiro
AU - Fukatsu, Atsushi
AU - Morozumi, Kunio
AU - Yoshikawa, Norishige
AU - Yuzawa, Yukio
AU - Matsuo, Seiichi
AU - Kiyohara, Yutaka
AU - Joh, Kensuke
AU - Taguchi, Takashi
AU - Makino, Hirofumi
N1 - Funding Information:
The authors greatly acknowledge the help and assistance of many colleagues in centers and affiliated hospitals with collecting the data. We also sincerely thank Ms. Mayumi Irie in the UNIN-INDICE for establishing and supporting the registration system of J-RBR. This study was supported by the committee grant from the Japanese Society of Nephrology and by a grant-in-aid from the Research Group on Progressive Renal Disease from the Ministry of Health, Labor and Welfare, Japan.
PY - 2011/8
Y1 - 2011/8
N2 - Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.
AB - Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the systemof the InternetData and Information Center forMedical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patients from 18 centers in 2007 and 1582 patients from 23 centers in 2008, including the affiliated hospitals. Renal biopsies were obtained from 726 native kidneys (88.8%) and 92 renal grafts (11.2%) in 2007, and 1400 native kidneys (88.5%) and 182 renal grafts (11.5%) in 2008. The most common clinical diagnosis was chronic nephritic syndrome (47.4%), followed by nephrotic syndrome (16.8%) and renal transplantation (11.2%) in 2007. A similar frequency of the clinical diagnoses was recognized in 2008. Of the native kidneys, the most frequent pathological diagnosis as classified by pathogenesis was immunoglobulin (Ig) A nephropathy (IgAN) both in 2007 (32.9%) and 2008 (30.2%). Among the primary glomerular diseases (except IgAN), membranous nephropathy (MN) was the most common disease both in 2007 (31.4%) and 2008 (25.7%). Conclusions In a cross-sectional study, the J-RBR has shown IgAN to be the most common disease in renal biopsies in 2007 and 2008, consistent with previous Japanese studies. MN predominated in the primary glomerular diseases (except for IgAN). The frequency of the disease and the clinical and demographic correlations should be investigated in further analyses by the J-RBR.
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U2 - 10.1007/s10157-011-0430-4
DO - 10.1007/s10157-011-0430-4
M3 - Review article
C2 - 21437579
AN - SCOPUS:80054740144
SN - 1342-1751
VL - 15
SP - 493
EP - 503
JO - Clinical and Experimental Nephrology
JF - Clinical and Experimental Nephrology
IS - 4
ER -