Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida

Diane C. Halstead, Timothy J. Sellen, Jennifer M. Adams-Haduch, Deborah A. Dossenback, Joan Abid, Yohei Doi, David L. Paterson

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Since 2001 there have been several reported outbreaks due to carbapenem-resistant Klebsiella pneumoniae (Kp), particularly in the northeastern states. Methods: Carbapenemase-producing Enterobacteriaceae from healthcare facilities in Northeast Florida were phenotypically identified and confirmed using PCR amplification and sequencing of the blaKPC gene. Results: Results from PFGE analysis of these isolates demonstrated possible horizontal spread from two possible "outbreak" strains during the study period. Conclusions: We present the first published cluster of Kp and Escherichia coli (Ec) cases in Florida carrying the KPC-2 or KPC-3 gene.

Original languageEnglish
Pages (from-to)680-687
Number of pages8
JournalSouthern Medical Journal
Volume102
Issue number7
DOIs
Publication statusPublished - 01-07-2009
Externally publishedYes

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Klebsiella pneumoniae
Enterobacteriaceae
Disease Outbreaks
Carbapenems
Genes
Escherichia coli
Delivery of Health Care
Polymerase Chain Reaction
carbapenemase

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Halstead, D. C., Sellen, T. J., Adams-Haduch, J. M., Dossenback, D. A., Abid, J., Doi, Y., & Paterson, D. L. (2009). Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida. Southern Medical Journal, 102(7), 680-687. https://doi.org/10.1097/SMJ.0b013e3181a93f9e
Halstead, Diane C. ; Sellen, Timothy J. ; Adams-Haduch, Jennifer M. ; Dossenback, Deborah A. ; Abid, Joan ; Doi, Yohei ; Paterson, David L. / Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida. In: Southern Medical Journal. 2009 ; Vol. 102, No. 7. pp. 680-687.
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Halstead, DC, Sellen, TJ, Adams-Haduch, JM, Dossenback, DA, Abid, J, Doi, Y & Paterson, DL 2009, 'Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida', Southern Medical Journal, vol. 102, no. 7, pp. 680-687. https://doi.org/10.1097/SMJ.0b013e3181a93f9e

Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida. / Halstead, Diane C.; Sellen, Timothy J.; Adams-Haduch, Jennifer M.; Dossenback, Deborah A.; Abid, Joan; Doi, Yohei; Paterson, David L.

In: Southern Medical Journal, Vol. 102, No. 7, 01.07.2009, p. 680-687.

Research output: Contribution to journalArticle

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AU - Sellen, Timothy J.

AU - Adams-Haduch, Jennifer M.

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AU - Abid, Joan

AU - Doi, Yohei

AU - Paterson, David L.

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