Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida

Diane C. Halstead, Timothy J. Sellen, Jennifer M. Adams-Haduch, Deborah A. Dossenback, Joan Abid, Yohei Doi, David L. Paterson

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Abstract

Background: Since 2001 there have been several reported outbreaks due to carbapenem-resistant Klebsiella pneumoniae (Kp), particularly in the northeastern states. Methods: Carbapenemase-producing Enterobacteriaceae from healthcare facilities in Northeast Florida were phenotypically identified and confirmed using PCR amplification and sequencing of the blaKPC gene. Results: Results from PFGE analysis of these isolates demonstrated possible horizontal spread from two possible "outbreak" strains during the study period. Conclusions: We present the first published cluster of Kp and Escherichia coli (Ec) cases in Florida carrying the KPC-2 or KPC-3 gene.

Original languageEnglish
Pages (from-to)680-687
Number of pages8
JournalSouthern Medical Journal
Volume102
Issue number7
DOIs
Publication statusPublished - 01-07-2009

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Halstead, D. C., Sellen, T. J., Adams-Haduch, J. M., Dossenback, D. A., Abid, J., Doi, Y., & Paterson, D. L. (2009). Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae, Northeast Florida. Southern Medical Journal, 102(7), 680-687. https://doi.org/10.1097/SMJ.0b013e3181a93f9e