Late hemorrhage from persistent pseudoaneurysm in vertebral artery dissection presenting with ischemia: Case report

Masachika Sagoh, Yuichi Hirose, Hideki Murakami, Kazunori Akaji, Masateru Katayama, Takuro Hayashi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

BACKGROUND: Vertebral artery dissection lesions tend to resolve spontaneously, but abnormal findings such as aneurysmal dilatation occasionally persist. However, the clinical features and pathological findings in such cases have never been verified. CASE DESCRIPTION: A 62-year- old man presented with left cerebellar infarction. Angiography showed the 'pearl and string sign' in the left vertebral artery, and he was diagnosed as having left vertebral artery dissection. Repeated angiography showed persistent aneurysmal dilatation with irregular stenosis. Eleven years after the cerebellar infarction, the patient presented with a subarachnoid hemorrhage from an aneurysm of the left vertebral artery, and the lesion was explored via the left suboccipital approach. The vertebral artery was firm, making the placement of a clip impossible, so the lesion was treated by coating of the bleeding point. The patient died of pneumonia and hyperglycemia on postoperative day 15. Postmortem examination revealed an organized intramural hematoma, thickening of the intima, and fibrous degeneration of the media of the vertebral artery, a fusiform, distended thin arterial wall with intimal disruption at the aneurysmal dilatation, and arteriosclerosis of all cerebral arteries. CONCLUSION: This case indicates that persistent aneurysmal dilatation of a dissection is a pseudoaneurysm prone to rupture, and that healing of the affected vessels might be severely compromised in the presence of pathological conditions such as arteriosclerosis and disturbed intraluminal blood flow in the dissected lesions.

Original languageEnglish
Pages (from-to)480-484
Number of pages5
JournalSurgical Neurology
Volume52
Issue number5
DOIs
Publication statusPublished - 01-11-1999
Externally publishedYes

Fingerprint

Vertebral Artery Dissection
Vertebral Artery
False Aneurysm
Dilatation
Ischemia
Hemorrhage
Arteriosclerosis
Infarction
Angiography
Tunica Intima
Cerebral Arteries
Subarachnoid Hemorrhage
Surgical Instruments
Hyperglycemia
Hematoma
Aneurysm
Dissection
Rupture
Autopsy
Pneumonia

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Surgery

Cite this

Sagoh, Masachika ; Hirose, Yuichi ; Murakami, Hideki ; Akaji, Kazunori ; Katayama, Masateru ; Hayashi, Takuro. / Late hemorrhage from persistent pseudoaneurysm in vertebral artery dissection presenting with ischemia : Case report. In: Surgical Neurology. 1999 ; Vol. 52, No. 5. pp. 480-484.
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Late hemorrhage from persistent pseudoaneurysm in vertebral artery dissection presenting with ischemia : Case report. / Sagoh, Masachika; Hirose, Yuichi; Murakami, Hideki; Akaji, Kazunori; Katayama, Masateru; Hayashi, Takuro.

In: Surgical Neurology, Vol. 52, No. 5, 01.11.1999, p. 480-484.

Research output: Contribution to journalArticle

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