Late potential as a predictor of re-hospitalization after percutaneous coronary intervention for acute coronary syndrome

Mari Nakamura, Koichiro Yoshioka, Mari Amino, Eiichi Watanabe, Toshiharu Fujii, Tadashi Hashida, Daisuke Fujibayashi, Shigetaka Kanda, Yoshinori Kobayashi, Teruhisa Tanabe, Yuji Ikari

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Abstract

Objective: The aim of this study was to investigate the significance of late potential (LP) after percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS). Method: We enrolled 135 consecutive patients with ACS admitted to Tokai University Hospital from February to December 2012. Twenty-four hour high-resolution ambulatory electrocardiogram was performed between post-PCI procedure and hospital discharge. The patients were divided into the LP-positive (33 patients) and LP-negative (102 patients) groups, and the relationship between LP and re-hospitalization was prospectively investigated. Results: The body mass index, serum creatinine, and creatine phosphokinase-MB were higher in the LP-positive group than in the LP-negative group (p < 0.05). The re-hospitalization rate was higher in the LP-positive group. (9 patients, 27.3% vs. 10 patients, 9.8%; p = 0.03). There were no significant differences in the occurrence of ventricular tachycardia or cardiac death between the groups. According to Kaplan-Maier analysis, proportion of re-hospitalization was significantly lower in the LP-positive group than in the LP-negative group (p = 0.01; average follow-up, 451.4 ± 25.9 days). The odds ratio of LP presence was 3.45 (highest among all variables; 95% confidence interval, 1.3-9.4; p < 0.01). Conclusion: Positive LP in patients with ACS after PCI may predict re-hospitalization.

Original languageEnglish
Pages (from-to)172-180
Number of pages9
JournalTokai Journal of Experimental and Clinical Medicine
Volume41
Issue number4
Publication statusPublished - 01-12-2016

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Percutaneous Coronary Intervention
Acute Coronary Syndrome
Hospitalization
Ventricular Tachycardia
Creatine Kinase
Creatinine
Electrocardiography
Body Mass Index
Odds Ratio
Confidence Intervals
Serum

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Nakamura, Mari ; Yoshioka, Koichiro ; Amino, Mari ; Watanabe, Eiichi ; Fujii, Toshiharu ; Hashida, Tadashi ; Fujibayashi, Daisuke ; Kanda, Shigetaka ; Kobayashi, Yoshinori ; Tanabe, Teruhisa ; Ikari, Yuji. / Late potential as a predictor of re-hospitalization after percutaneous coronary intervention for acute coronary syndrome. In: Tokai Journal of Experimental and Clinical Medicine. 2016 ; Vol. 41, No. 4. pp. 172-180.
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abstract = "Objective: The aim of this study was to investigate the significance of late potential (LP) after percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS). Method: We enrolled 135 consecutive patients with ACS admitted to Tokai University Hospital from February to December 2012. Twenty-four hour high-resolution ambulatory electrocardiogram was performed between post-PCI procedure and hospital discharge. The patients were divided into the LP-positive (33 patients) and LP-negative (102 patients) groups, and the relationship between LP and re-hospitalization was prospectively investigated. Results: The body mass index, serum creatinine, and creatine phosphokinase-MB were higher in the LP-positive group than in the LP-negative group (p < 0.05). The re-hospitalization rate was higher in the LP-positive group. (9 patients, 27.3{\%} vs. 10 patients, 9.8{\%}; p = 0.03). There were no significant differences in the occurrence of ventricular tachycardia or cardiac death between the groups. According to Kaplan-Maier analysis, proportion of re-hospitalization was significantly lower in the LP-positive group than in the LP-negative group (p = 0.01; average follow-up, 451.4 ± 25.9 days). The odds ratio of LP presence was 3.45 (highest among all variables; 95{\%} confidence interval, 1.3-9.4; p < 0.01). Conclusion: Positive LP in patients with ACS after PCI may predict re-hospitalization.",
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Nakamura, M, Yoshioka, K, Amino, M, Watanabe, E, Fujii, T, Hashida, T, Fujibayashi, D, Kanda, S, Kobayashi, Y, Tanabe, T & Ikari, Y 2016, 'Late potential as a predictor of re-hospitalization after percutaneous coronary intervention for acute coronary syndrome', Tokai Journal of Experimental and Clinical Medicine, vol. 41, no. 4, pp. 172-180.

Late potential as a predictor of re-hospitalization after percutaneous coronary intervention for acute coronary syndrome. / Nakamura, Mari; Yoshioka, Koichiro; Amino, Mari; Watanabe, Eiichi; Fujii, Toshiharu; Hashida, Tadashi; Fujibayashi, Daisuke; Kanda, Shigetaka; Kobayashi, Yoshinori; Tanabe, Teruhisa; Ikari, Yuji.

In: Tokai Journal of Experimental and Clinical Medicine, Vol. 41, No. 4, 01.12.2016, p. 172-180.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Late potential as a predictor of re-hospitalization after percutaneous coronary intervention for acute coronary syndrome

AU - Nakamura, Mari

AU - Yoshioka, Koichiro

AU - Amino, Mari

AU - Watanabe, Eiichi

AU - Fujii, Toshiharu

AU - Hashida, Tadashi

AU - Fujibayashi, Daisuke

AU - Kanda, Shigetaka

AU - Kobayashi, Yoshinori

AU - Tanabe, Teruhisa

AU - Ikari, Yuji

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Objective: The aim of this study was to investigate the significance of late potential (LP) after percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS). Method: We enrolled 135 consecutive patients with ACS admitted to Tokai University Hospital from February to December 2012. Twenty-four hour high-resolution ambulatory electrocardiogram was performed between post-PCI procedure and hospital discharge. The patients were divided into the LP-positive (33 patients) and LP-negative (102 patients) groups, and the relationship between LP and re-hospitalization was prospectively investigated. Results: The body mass index, serum creatinine, and creatine phosphokinase-MB were higher in the LP-positive group than in the LP-negative group (p < 0.05). The re-hospitalization rate was higher in the LP-positive group. (9 patients, 27.3% vs. 10 patients, 9.8%; p = 0.03). There were no significant differences in the occurrence of ventricular tachycardia or cardiac death between the groups. According to Kaplan-Maier analysis, proportion of re-hospitalization was significantly lower in the LP-positive group than in the LP-negative group (p = 0.01; average follow-up, 451.4 ± 25.9 days). The odds ratio of LP presence was 3.45 (highest among all variables; 95% confidence interval, 1.3-9.4; p < 0.01). Conclusion: Positive LP in patients with ACS after PCI may predict re-hospitalization.

AB - Objective: The aim of this study was to investigate the significance of late potential (LP) after percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS). Method: We enrolled 135 consecutive patients with ACS admitted to Tokai University Hospital from February to December 2012. Twenty-four hour high-resolution ambulatory electrocardiogram was performed between post-PCI procedure and hospital discharge. The patients were divided into the LP-positive (33 patients) and LP-negative (102 patients) groups, and the relationship between LP and re-hospitalization was prospectively investigated. Results: The body mass index, serum creatinine, and creatine phosphokinase-MB were higher in the LP-positive group than in the LP-negative group (p < 0.05). The re-hospitalization rate was higher in the LP-positive group. (9 patients, 27.3% vs. 10 patients, 9.8%; p = 0.03). There were no significant differences in the occurrence of ventricular tachycardia or cardiac death between the groups. According to Kaplan-Maier analysis, proportion of re-hospitalization was significantly lower in the LP-positive group than in the LP-negative group (p = 0.01; average follow-up, 451.4 ± 25.9 days). The odds ratio of LP presence was 3.45 (highest among all variables; 95% confidence interval, 1.3-9.4; p < 0.01). Conclusion: Positive LP in patients with ACS after PCI may predict re-hospitalization.

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