LD for pancreas transplantation

Takashi Kenmochi, Takehide Asano, Taihei Ito

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The first extrarenal organ to be successfully transplanted using living donors was the pancreas. The first pancreas transplantation using a living donor (LDP) was performed on June 20, 1979, at the University of Minnesota [1, 2]. Furthermore, successful simultaneous pancreas and kidney transplantation from a living donor (LDSPK) was started in 1994 also at the University of Minnesota [3]. The outcome of LDPs performed at the University of Minnesota demonstrated that the segmental pancreas was able to normalize plasma glucose levels and realize an insulin independency in the severe diabetic patients. The outcome of the donors was considered to be acceptable when using the stringent donor criteria concerning the endocrine function [4]. Based on a severe shortage of the deceased donors in our country and the satisfactory outcome of LDPs at the University of Minnesota, we have firstly introduced LDP (LDSPK) in our country on January 7, 2004 [5]. Eighteen LDPs (16 LDSPKs) have, so far, been performed in Chiba-East National Hospital. From 2007, we have introduced LDSPK from ABO-incompatible living donors according to our successful desensitization and immunosuppression protocol for ABO-incompatible kidney transplantation and performed, so far, six cases. In this chapter, we describe the criteria for living donation, historical background, and the prognosis for living donor from our clinical experiences of sixteen LDSPKs.

Original languageEnglish
Title of host publicationMarginal Donors
Subtitle of host publicationCurrent and Future Status
PublisherSpringer Japan
Pages225-234
Number of pages10
ISBN (Electronic)9784431544845
ISBN (Print)4431544836, 9784431544838
DOIs
Publication statusPublished - 01-12-2013

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Fingerprint Dive into the research topics of 'LD for pancreas transplantation'. Together they form a unique fingerprint.

  • Cite this

    Kenmochi, T., Asano, T., & Ito, T. (2013). LD for pancreas transplantation. In Marginal Donors: Current and Future Status (pp. 225-234). Springer Japan. https://doi.org/10.1007/978-4-431-54484-5_20