Abstract
The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.
| Original language | English |
|---|---|
| Pages (from-to) | 44-47 |
| Number of pages | 4 |
| Journal | International Journal of Infectious Diseases |
| Volume | 84 |
| DOIs | |
| Publication status | Published - 07-2019 |
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All Science Journal Classification (ASJC) codes
- Microbiology (medical)
- Infectious Diseases
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}
Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns. / Harada, Sohei; Aoki, Kotaro; Okamoto, Koh; Kinoshita, Osamu; Nawata, Kan; Ishii, Yoshikazu; Tateda, Kazuhiro; Sasaki, Masakazu; Saga, Tomoo; Doi, Yohei; Yotsuyanagi, Hiroshi; Moriya, Kyoji; Ono, Minoru.
In: International Journal of Infectious Diseases, Vol. 84, 07.2019, p. 44-47.Research output: Contribution to journal › Article
TY - JOUR
T1 - Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns
AU - Harada, Sohei
AU - Aoki, Kotaro
AU - Okamoto, Koh
AU - Kinoshita, Osamu
AU - Nawata, Kan
AU - Ishii, Yoshikazu
AU - Tateda, Kazuhiro
AU - Sasaki, Masakazu
AU - Saga, Tomoo
AU - Doi, Yohei
AU - Yotsuyanagi, Hiroshi
AU - Moriya, Kyoji
AU - Ono, Minoru
PY - 2019/7
Y1 - 2019/7
N2 - The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.
AB - The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.
UR - http://www.scopus.com/inward/record.url?scp=85065861307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065861307&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2019.05.001
DO - 10.1016/j.ijid.2019.05.001
M3 - Article
C2 - 31075509
AN - SCOPUS:85065861307
VL - 84
SP - 44
EP - 47
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
SN - 1201-9712
ER -