Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns

Sohei Harada, Kotaro Aoki, Koh Okamoto, Osamu Kinoshita, Kan Nawata, Yoshikazu Ishii, Kazuhiro Tateda, Masakazu Sasaki, Tomoo Saga, Yohei Doi, Hiroshi Yotsuyanagi, Kyoji Moriya, Minoru Ono

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.

Original languageEnglish
Pages (from-to)44-47
Number of pages4
JournalInternational Journal of Infectious Diseases
Volume84
DOIs
Publication statusPublished - 07-2019

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns'. Together they form a unique fingerprint.

Cite this