Abstract
Epstein-Barr virus (EBV) is a member of gamma-herpesvirus, which can cause various types of tumor. Coexisting with the host for a long period of time, it has evolved unique and sophisticated strategy for survival by taking complicated, tactical modes of infection. Such modes include latent and lytic infections, and latent state is further categorized into four types. Differences and transitions in such lifestyles are significantly associated not only with virus amplification, but also with pathology and advancement of the disorders. I here review oncogenesis and pathogenesis of EBV-related disorders, especially focusing on our recent results on the modes of EBV infection.
| Original language | English |
|---|---|
| Pages (from-to) | 95-104 |
| Number of pages | 10 |
| Journal | Uirusu |
| Volume | 64 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 01-01-2014 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Lifecycles of EBV and cancer. / Murata, Takayuki.
In: Uirusu, Vol. 64, No. 1, 01.01.2014, p. 95-104.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Lifecycles of EBV and cancer
AU - Murata, Takayuki
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Epstein-Barr virus (EBV) is a member of gamma-herpesvirus, which can cause various types of tumor. Coexisting with the host for a long period of time, it has evolved unique and sophisticated strategy for survival by taking complicated, tactical modes of infection. Such modes include latent and lytic infections, and latent state is further categorized into four types. Differences and transitions in such lifestyles are significantly associated not only with virus amplification, but also with pathology and advancement of the disorders. I here review oncogenesis and pathogenesis of EBV-related disorders, especially focusing on our recent results on the modes of EBV infection.
AB - Epstein-Barr virus (EBV) is a member of gamma-herpesvirus, which can cause various types of tumor. Coexisting with the host for a long period of time, it has evolved unique and sophisticated strategy for survival by taking complicated, tactical modes of infection. Such modes include latent and lytic infections, and latent state is further categorized into four types. Differences and transitions in such lifestyles are significantly associated not only with virus amplification, but also with pathology and advancement of the disorders. I here review oncogenesis and pathogenesis of EBV-related disorders, especially focusing on our recent results on the modes of EBV infection.
UR - http://www.scopus.com/inward/record.url?scp=84946215832&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84946215832&partnerID=8YFLogxK
U2 - 10.2222/jsv.64.95
DO - 10.2222/jsv.64.95
M3 - Review article
VL - 64
SP - 95
EP - 104
JO - Uirusu. Journal of virology
JF - Uirusu. Journal of virology
SN - 0042-6857
IS - 1
ER -