Lipstick dermatitis due to C18 aliphatic compounds

Ritsuko Hayakawa, Kayoko Matsunaga, Mari Suzuki, Yaeno Arima, Yukari Ohkido

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19 Citations (Scopus)


An 18‐year‐old girl developed cheilitis. She had a past history of lip cream dermatitis, but the cause was not found. Patch tests with 2 lipsticks were strongly positive. Tests with the ingredients were positive to 2 aliphatic compounds, glyceryl diisostearate and diisostearyl malate. Impurities in the materials were suspected as the cause. Analysis by gas chromatography detected 3 chemicals in glyceryl diisostearate and 1 in diisostearyl malate as impurities. Patch testing with the impurities and glyceryl monoisostearate 0.01% pet in glyceryl diisostearate and isostearyl alcohol 0.25% pet in diisostearyl malate were strongly positive. The characteristics common to the 2 chemicals were liquidity at room temperature, branched C18aliphatic compound and primary alcohol. Chemicals lacking any of the above 3 features did not react.

Original languageEnglish
Pages (from-to)215-219
Number of pages5
JournalContact Dermatitis
Issue number4
Publication statusPublished - 04-1987
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Dermatology


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