Locomotion Outcome in Hemiplegic Patients with Middle Cerebral Artery Infarction: The Difference Between Right- and Left-Sided Lesions

Atsuko Goto, Satoshi Okuda, Shinji Ito, Yukihiko Matsuoka, Eiichi Ito, Akira Takahashi, Gen Sobue

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: This study was performed to analyze the locomotion outcome of hemiplegic patients with stroke and to explore the factors influencing it. Methods: A total of 247 patients (mean age 65.6 ± 10.5 years) admitted to our hospital for rehabilitation were included in the study. Their cardinal neurologic sign was hemiplegia caused by infarction in the middle cerebral artery as a result of a first stroke. When rehabilitation programs were completed, the final motor outcome was evaluated and compared between patients with right and left hemispheric infarct. In addition, the following items were analyzed: size, location, and subtype of the infarct; hemispatial neglect and aphasia; cerebral blood flow (CBF); and periventricular lucency on computed tomography scan. Results: (1) There was a negative relationship between the infarct size and the locomotion outcome. The difference in locomotion outcome was not significant between the patients with infarction of the perforating arteries and those of the cortical arteries. No significant difference in the locomotion outcome was found between the patients with an atherothrombotic or cardioembolic infarction. (2) In spite of the existence of hemispatial neglect or aphasia, the patients with a right-sided infarction were significantly inferior to patients with a left-sided one in locomotion outcome, except for those with a large infarction. (3) In patients with infarction in the territory of the perforating arteries, there was a negative relationship between the area of decreased CBF or periventricular lucency and the locomotion outcome. When the area of decreased CBF on the homolateral hemisphere involving the infarction extended to less than or equal to two cerebral lobes, the locomotion outcome was significantly worse in the patients with a right-sided infarction. Conclusions: Overall, for the patients with middle cerebral artery infarction, the locomotion outcome was poorer in patients with a right hemispheric infarction than a left-sided one, except in the case of a large infarction.

Original languageEnglish
Pages (from-to)60-67
Number of pages8
JournalJournal of Stroke and Cerebrovascular Diseases
Volume18
Issue number1
DOIs
Publication statusPublished - 01-01-2009
Externally publishedYes

Fingerprint

Middle Cerebral Artery Infarction
Locomotion
Infarction
Cerebrovascular Circulation
Perceptual Disorders
Arteries
Aphasia
Rehabilitation
Stroke
Hemiplegia
Patient Rights
Neurologic Manifestations
Tomography

All Science Journal Classification (ASJC) codes

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Goto, Atsuko ; Okuda, Satoshi ; Ito, Shinji ; Matsuoka, Yukihiko ; Ito, Eiichi ; Takahashi, Akira ; Sobue, Gen. / Locomotion Outcome in Hemiplegic Patients with Middle Cerebral Artery Infarction : The Difference Between Right- and Left-Sided Lesions. In: Journal of Stroke and Cerebrovascular Diseases. 2009 ; Vol. 18, No. 1. pp. 60-67.
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Locomotion Outcome in Hemiplegic Patients with Middle Cerebral Artery Infarction : The Difference Between Right- and Left-Sided Lesions. / Goto, Atsuko; Okuda, Satoshi; Ito, Shinji; Matsuoka, Yukihiko; Ito, Eiichi; Takahashi, Akira; Sobue, Gen.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 18, No. 1, 01.01.2009, p. 60-67.

Research output: Contribution to journalArticle

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T1 - Locomotion Outcome in Hemiplegic Patients with Middle Cerebral Artery Infarction

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AU - Goto, Atsuko

AU - Okuda, Satoshi

AU - Ito, Shinji

AU - Matsuoka, Yukihiko

AU - Ito, Eiichi

AU - Takahashi, Akira

AU - Sobue, Gen

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AB - Objective: This study was performed to analyze the locomotion outcome of hemiplegic patients with stroke and to explore the factors influencing it. Methods: A total of 247 patients (mean age 65.6 ± 10.5 years) admitted to our hospital for rehabilitation were included in the study. Their cardinal neurologic sign was hemiplegia caused by infarction in the middle cerebral artery as a result of a first stroke. When rehabilitation programs were completed, the final motor outcome was evaluated and compared between patients with right and left hemispheric infarct. In addition, the following items were analyzed: size, location, and subtype of the infarct; hemispatial neglect and aphasia; cerebral blood flow (CBF); and periventricular lucency on computed tomography scan. Results: (1) There was a negative relationship between the infarct size and the locomotion outcome. The difference in locomotion outcome was not significant between the patients with infarction of the perforating arteries and those of the cortical arteries. No significant difference in the locomotion outcome was found between the patients with an atherothrombotic or cardioembolic infarction. (2) In spite of the existence of hemispatial neglect or aphasia, the patients with a right-sided infarction were significantly inferior to patients with a left-sided one in locomotion outcome, except for those with a large infarction. (3) In patients with infarction in the territory of the perforating arteries, there was a negative relationship between the area of decreased CBF or periventricular lucency and the locomotion outcome. When the area of decreased CBF on the homolateral hemisphere involving the infarction extended to less than or equal to two cerebral lobes, the locomotion outcome was significantly worse in the patients with a right-sided infarction. Conclusions: Overall, for the patients with middle cerebral artery infarction, the locomotion outcome was poorer in patients with a right hemispheric infarction than a left-sided one, except in the case of a large infarction.

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