Long-term durability of pericardial valves in the aortic position in younger patients: When does reoperation become necessary?

Kenji Minakata, Shiro Tanaka, Yoshiharu Takahara, Tatsuo Kaneko, Akihiko Usui, Mitsuomi Shimamoto, Yohei Okawa, Hitoshi Yaku, Kazuo Yamanaka, Nobushige Tamura, Ryuzo Sakata

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Background We sought to assess the long-term durability of pericardial valves in patients at age <65 years undergoing aortic valve replacement (AVR), and to determine the timing of redo operations due to structural valve deterioration (SVD). Methods From 1986 to 2001, a total of 574 adult patients underwent AVR with pericardial valves in nine hospitals in Japan. Of these, 53 patients were at age <65 years (group Y). These patients were compared with those of age ≥65 (group O, n = 521). Results The mean follow-up duration was 9.5 years in group Y and 8.1 years in group O. Freedom from reoperation due to SVD was 100% at five years, 90.8% at 10 years, and 47.2% at 15 years in group Y, and 99.3% at five years, 97.4% at 10 years, and 94.4% at 15 years in group O (log-rank test, p < 0.01). In those who required redo AVR in group Y (n = 12), the mean time from initial operation to reoperation was 12.1 years. The reoperation-free survival curve started to decline after eight years postoperation in group Y. Conclusions Redo AVR started to become necessary eight years after surgery in the patients who underwent AVR with pericardial valve at age <65 years. In addition, approximately half of those patients required reoperation due to SVD by 15 years postoperatively.

Original languageEnglish
Pages (from-to)405-413
Number of pages9
JournalJournal of Cardiac Surgery
Volume30
Issue number5
DOIs
Publication statusPublished - 01-05-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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