Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity

Kota Ishikawa, Shin Tsunekawa, Makoto Ikeniwa, Takako Izumoto, Atsushi Iida, Hidetada Ogata, Eita Uenishi, Yusuke Seino, Nobuaki Ozaki, Yoshihisa Sugimura, Yoji Hamada, Akio Kuroda, Keiko Shinjo, Yutaka Kondo, Yutaka Oiso

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology