Long-term surgical outcome of noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma of the pancreas

Toshio Nakagohri, Takehide Asano, Takashi Kenmochi, Tetsuro Urashima, Takenori Ochiai

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Abstract

The objective of this study was to clarify the long-term outcome after surgical resection in patients with noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma. We performed a retrospective review of the clinicopathological features and outcome in patients who underwent pancreatic resection for noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma between November 1982 and December 1997 at Chiba University Hospital. Minimally invasive structures were pathologically observed in five cases. The mean age of patients with either noninvasive (n = 16) or minimally invasive (n = 5) adenocarcinoma was 61 years. Of the patients with minimally invasive adenocarcinoma, 4 had abdominal pain. Conversely, 7 patients with noninvasive adenocarcinoma had no complaint. The mean size of noninvasive and minimally invasive tumors was 2.5 cm (range 0.8 to 4.0) and 3.3 cm (range 2.5 to 4.5), respectively. The overall 5-year and 10-year survival rates for all 21 patients were 89% and 47%, respectively. Disease recurred in 3 patients; 2 patients with minimally invasive adenocarcinoma and 1 with noninvasive adenocarcinoma. Recurrence sites were peritoneum (n = 2) and main pancreatic duct of the remnant pancreas (n = 1); 5 disease-free patients died of unrelated causes. The remaining 13 patients are alive and disease free 3 to 12 years after surgery. Noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma had a favorable prognosis after surgical treatment.

Original languageEnglish
Pages (from-to)1166-1169
Number of pages4
JournalWorld Journal of Surgery
Volume26
Issue number9
DOIs
Publication statusPublished - 01-09-2002
Externally publishedYes

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Papillary Adenocarcinoma
Mucinous Adenocarcinoma
Pancreas
Adenocarcinoma
Pancreatic Ducts
Peritoneum
Abdominal Pain
Survival Rate

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Nakagohri, Toshio ; Asano, Takehide ; Kenmochi, Takashi ; Urashima, Tetsuro ; Ochiai, Takenori. / Long-term surgical outcome of noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma of the pancreas. In: World Journal of Surgery. 2002 ; Vol. 26, No. 9. pp. 1166-1169.
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Long-term surgical outcome of noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma of the pancreas. / Nakagohri, Toshio; Asano, Takehide; Kenmochi, Takashi; Urashima, Tetsuro; Ochiai, Takenori.

In: World Journal of Surgery, Vol. 26, No. 9, 01.09.2002, p. 1166-1169.

Research output: Contribution to journalArticle

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