TY - JOUR
T1 - Low dose chest CT protocol (50 mAs) as a routine protocol for comprehensive assessment of intrathoracic abnormality
AU - iLEAD study group
AU - Kubo, Takeshi
AU - Ohno, Yoshiharu
AU - Nishino, Mizuki
AU - Lin, Pei Jan
AU - Gautam, Shiva
AU - Kauczor, Hans Ulrich
AU - Hatabu, Hiroto
N1 - Publisher Copyright:
© 2016.
PY - 2016
Y1 - 2016
N2 - Purpose: To determine the diagnostic capability of low-dose CT (50 mAs) in comparison to standard-dose CT (150 mAs). Materials and methods: Fifty-nine consecutive patients underwent two non-contrast chest CT scans with different current-time products (50 and 150 mAs at 120 kVp) on a 64-detector row CT scanner. Three board certified chest radiologists independently reviewed 118 series of 2 mm-thick images (2 series for each of 59 patients) in a random order. The readers assessed abnormal findings including emphysema, ground-glass opacity, reticular opacity, micronodules, bronchiectasis, honeycomb, nodules (>5 mm), aortic aneurysm, coronary artery calcification, pericardial and pleural effusion, pleural thickening, mediastinal tumor and lymph node enlargement. Five-point scale from 1 (definitely absent) to 5 (definitely present) was used to record the results. The rates of score agreement between two images were calculated. Deviation of one observer's score from other two observers was compared between low dose CT and standard dose CT. Results: Mean agreement rate of the lung parenchymal findings between low dose CT and standard dose CT images was 0.836 (range, 0.746-0.926). Mean agreement rates for mediastinal and pleural findings were 0.920 (range, 0.735-1.000). There was no statistically significant difference in the deviation of the observers' scores between low-dose CT and standard-dose CT. Conclusion: Low dose CT protocol at 50 mAs can produce the screening results consistent with standard dose CT protocol (150 mAs), supporting routine use of low dose chest CT protocol.
AB - Purpose: To determine the diagnostic capability of low-dose CT (50 mAs) in comparison to standard-dose CT (150 mAs). Materials and methods: Fifty-nine consecutive patients underwent two non-contrast chest CT scans with different current-time products (50 and 150 mAs at 120 kVp) on a 64-detector row CT scanner. Three board certified chest radiologists independently reviewed 118 series of 2 mm-thick images (2 series for each of 59 patients) in a random order. The readers assessed abnormal findings including emphysema, ground-glass opacity, reticular opacity, micronodules, bronchiectasis, honeycomb, nodules (>5 mm), aortic aneurysm, coronary artery calcification, pericardial and pleural effusion, pleural thickening, mediastinal tumor and lymph node enlargement. Five-point scale from 1 (definitely absent) to 5 (definitely present) was used to record the results. The rates of score agreement between two images were calculated. Deviation of one observer's score from other two observers was compared between low dose CT and standard dose CT. Results: Mean agreement rate of the lung parenchymal findings between low dose CT and standard dose CT images was 0.836 (range, 0.746-0.926). Mean agreement rates for mediastinal and pleural findings were 0.920 (range, 0.735-1.000). There was no statistically significant difference in the deviation of the observers' scores between low-dose CT and standard-dose CT. Conclusion: Low dose CT protocol at 50 mAs can produce the screening results consistent with standard dose CT protocol (150 mAs), supporting routine use of low dose chest CT protocol.
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U2 - 10.1016/j.ejro.2016.04.001
DO - 10.1016/j.ejro.2016.04.001
M3 - Article
AN - SCOPUS:84964470904
SN - 2352-0477
VL - 3
SP - 86
EP - 94
JO - European Journal of Radiology Open
JF - European Journal of Radiology Open
ER -