Abstract
Glass catfish (Kryptopterus bicirrhus) have transparent muscles and skin. Intramuscular injection of DNA encoding luciferase into these fish induced luciferase expression that was measurable in vivo with a low light video image analyser. Expression could be detected up to at least 2 years after DNA injection. Although luciferase is not representative of all types of antigen, this study stresses the need for future studies directed to limit the period of antigen expression after DNA vaccination.
| Original language | English |
|---|---|
| Pages (from-to) | 199-202 |
| Number of pages | 4 |
| Journal | Fish and Shellfish Immunology |
| Volume | 11 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 02-2001 |
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All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Aquatic Science
Cite this
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Luciferase expression 2 years after DNA injection in glass catfish (Kryptopterus bicirrhus). / Dijkstra, J. M.; Okamoto, H.; Ototake, M.; Nakanishi, T.
In: Fish and Shellfish Immunology, Vol. 11, No. 2, 02.2001, p. 199-202.Research output: Contribution to journal › Article
TY - JOUR
T1 - Luciferase expression 2 years after DNA injection in glass catfish (Kryptopterus bicirrhus)
AU - Dijkstra, J. M.
AU - Okamoto, H.
AU - Ototake, M.
AU - Nakanishi, T.
PY - 2001/2
Y1 - 2001/2
N2 - Glass catfish (Kryptopterus bicirrhus) have transparent muscles and skin. Intramuscular injection of DNA encoding luciferase into these fish induced luciferase expression that was measurable in vivo with a low light video image analyser. Expression could be detected up to at least 2 years after DNA injection. Although luciferase is not representative of all types of antigen, this study stresses the need for future studies directed to limit the period of antigen expression after DNA vaccination.
AB - Glass catfish (Kryptopterus bicirrhus) have transparent muscles and skin. Intramuscular injection of DNA encoding luciferase into these fish induced luciferase expression that was measurable in vivo with a low light video image analyser. Expression could be detected up to at least 2 years after DNA injection. Although luciferase is not representative of all types of antigen, this study stresses the need for future studies directed to limit the period of antigen expression after DNA vaccination.
UR - http://www.scopus.com/inward/record.url?scp=0035259203&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035259203&partnerID=8YFLogxK
U2 - 10.1006/fsim.2000.0303
DO - 10.1006/fsim.2000.0303
M3 - Article
C2 - 11308080
AN - SCOPUS:0035259203
VL - 11
SP - 199
EP - 202
JO - Fish and Shellfish Immunology
JF - Fish and Shellfish Immunology
SN - 1050-4648
IS - 2
ER -