Luciferase expression 2 years after DNA injection in glass catfish (Kryptopterus bicirrhus)

J. M. Dijkstra, H. Okamoto, M. Ototake, T. Nakanishi

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Glass catfish (Kryptopterus bicirrhus) have transparent muscles and skin. Intramuscular injection of DNA encoding luciferase into these fish induced luciferase expression that was measurable in vivo with a low light video image analyser. Expression could be detected up to at least 2 years after DNA injection. Although luciferase is not representative of all types of antigen, this study stresses the need for future studies directed to limit the period of antigen expression after DNA vaccination.

Original languageEnglish
Pages (from-to)199-202
Number of pages4
JournalFish and Shellfish Immunology
Volume11
Issue number2
DOIs
Publication statusPublished - 02-2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Aquatic Science

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