TY - JOUR
T1 - Macular hole development in fellow eyes of patients with unilateral macular hole
AU - Niwa, Hideyasu
AU - Terasaki, Hiroko
AU - Ito, Yasuki
AU - Miyake, Yozo
N1 - Funding Information:
This study was supported by grants-in-aid 16390497 (H.T.) and 15790982 (Y.I.) from the Ministry of Education, Science, and Culture, Tokyo, Japan.
PY - 2005/9
Y1 - 2005/9
N2 - • PURPOSE: To determine the incidence of developing an idiopathic full-thickness macular hole in fellow eyes that have vitreofoveal attachments and perifoveal vitreous detachment in patients with unilateral idiopathic macular hole. • DESIGN: Retrospective cross-sectional observational study. • METHODS: The fellow eyes of 201 patients with full-thickness macular holes were examined by optical coherence tomography (OCT). A subset of 58 fellow eyes with vitreofoveal attachments and perifoveal vitreous detachment was observed during follow-up, and the changes in the vitreofoveal attachment within 24 months from the initial OCT examination were investigated. • RESULTS: In the 58 eyes, the vitreofoveal relationship changed in 27 eyes. Among the 27 eyes, three eyes developed a full-thickness macular hole, and the other 24 eyes developed a posterior vitreous detachment only over the fovea or a complete posterior vitreous detachment without macular hole formation. The vitreofoveal relationship did not change in 31 eyes during the 24-month period. • CONCLUSION: From an analysis of the changes in the vitreoretinal relationship identified by OCT, three (11%) of 27 fellow eyes in patients with unilateral idiopathic macular hole developed a full-thickness macular hole.
AB - • PURPOSE: To determine the incidence of developing an idiopathic full-thickness macular hole in fellow eyes that have vitreofoveal attachments and perifoveal vitreous detachment in patients with unilateral idiopathic macular hole. • DESIGN: Retrospective cross-sectional observational study. • METHODS: The fellow eyes of 201 patients with full-thickness macular holes were examined by optical coherence tomography (OCT). A subset of 58 fellow eyes with vitreofoveal attachments and perifoveal vitreous detachment was observed during follow-up, and the changes in the vitreofoveal attachment within 24 months from the initial OCT examination were investigated. • RESULTS: In the 58 eyes, the vitreofoveal relationship changed in 27 eyes. Among the 27 eyes, three eyes developed a full-thickness macular hole, and the other 24 eyes developed a posterior vitreous detachment only over the fovea or a complete posterior vitreous detachment without macular hole formation. The vitreofoveal relationship did not change in 31 eyes during the 24-month period. • CONCLUSION: From an analysis of the changes in the vitreoretinal relationship identified by OCT, three (11%) of 27 fellow eyes in patients with unilateral idiopathic macular hole developed a full-thickness macular hole.
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U2 - 10.1016/j.ajo.2005.03.070
DO - 10.1016/j.ajo.2005.03.070
M3 - Article
C2 - 16084790
AN - SCOPUS:24044442335
SN - 0002-9394
VL - 140
SP - 370
EP - 375
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -