TY - JOUR
T1 - Maitotoxin, A Presumed Calcium Channel Activator, Induces the Acrosome Reaction in Mussel Spermatozoa
T2 - maitotoxin/acrosome reaction/calcium channel activator/calcium channel antagonist/mussel sperm
AU - NISHIYAMA, ICHIRO
AU - MATSUI, TAEI
AU - YASUMOTO, TAKESHI
AU - OSHIO, SHIGERU
AU - HOSHI, MOTONORI
PY - 1986/9
Y1 - 1986/9
N2 - Maitotoxin, a presumed activator of the voltage‐sensitive calcium channel, induced the acrosome reaction in the mussel, Mytilus edulis at physiological pH and in the starfish, Asterias amurensis at pH 9.5. The induction of acrosome reaction by maitotoxin depended upon external Ca2+ and was inhibited by two types of calcium channel blockers; verapamil and diltiazem. These results suggest that the activation of the voltage‐sensitive calcium channel takes an important part in the initiation of acrosome reaction in Mytilus and other animals.
AB - Maitotoxin, a presumed activator of the voltage‐sensitive calcium channel, induced the acrosome reaction in the mussel, Mytilus edulis at physiological pH and in the starfish, Asterias amurensis at pH 9.5. The induction of acrosome reaction by maitotoxin depended upon external Ca2+ and was inhibited by two types of calcium channel blockers; verapamil and diltiazem. These results suggest that the activation of the voltage‐sensitive calcium channel takes an important part in the initiation of acrosome reaction in Mytilus and other animals.
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U2 - 10.1111/j.1440-169X.1986.00443.x
DO - 10.1111/j.1440-169X.1986.00443.x
M3 - Article
AN - SCOPUS:0022996373
SN - 0012-1592
VL - 28
SP - 443
EP - 448
JO - Development, Growth & Differentiation
JF - Development, Growth & Differentiation
IS - 5
ER -