TY - JOUR
T1 - Major and minor histocompatibility antigens in allogeneic hematopoietic stem cell transplantation
AU - Akatsuka, Yoshiki
AU - Morishima, Yasuo
PY - 2004
Y1 - 2004
N2 - The critical role of molecular biology-based HLA allele matching for transplant-related immunologic events has been demonstrated. Potential applications of hematopoietic cell-specific minor histocompatibility antigens to immunotherapy by selectively augmenting the graft-versus-leukemia/lymphoma effect have been studied. These extensive efforts will increase the number of patients who can benefit from allogeneic HSCT over HLA disparity, or from active and selective immunotherapy, or both. 71.
AB - The critical role of molecular biology-based HLA allele matching for transplant-related immunologic events has been demonstrated. Potential applications of hematopoietic cell-specific minor histocompatibility antigens to immunotherapy by selectively augmenting the graft-versus-leukemia/lymphoma effect have been studied. These extensive efforts will increase the number of patients who can benefit from allogeneic HSCT over HLA disparity, or from active and selective immunotherapy, or both. 71.
KW - Allogeneic hematopoietic stem cell transplantation
KW - HLA
KW - Killer cell Ig-like receptor
KW - Minor histocompatibility antigen
UR - http://www.scopus.com/inward/record.url?scp=77950086293&partnerID=8YFLogxK
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U2 - 10.1097/00075200-200403000-00013
DO - 10.1097/00075200-200403000-00013
M3 - Review article
AN - SCOPUS:77950086293
SN - 1087-2418
VL - 9
SP - 64
EP - 71
JO - Current Opinion in Organ Transplantation
JF - Current Opinion in Organ Transplantation
IS - 1
ER -