Abstract
Background: The therapeutic strategy for giant cell myocarditis (GCM) remains controversial, so we reviewed the clinical status of Japanese patients with GCM. Methods and Results: We retrospectively reviewed 6 consecutive patients with GCM requiring percutaneous mechanical circulatory support (p-MCS), with 3 further requiring ventricular assist devices. One patient died during p-MCS. Cardiac function improved in the other 5 with immunosuppressive therapy, but only 3 patients treated with dual immunosuppressants, including cyclosporine (CyA), achieved >1-year survival. Conclusions: The prognosis of patients with fulminant GCM is poor, but a treatment that combines MCS and early administration of CyA-based immunosuppressants will be useful.
Original language | English |
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Pages (from-to) | 815-819 |
Number of pages | 5 |
Journal | Circulation Journal |
Volume | 84 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2020 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine