Metachronous multiple carcinomas arising at a colostomy site 15 years after abdominoperineal resection: A case report and review of Japanese literature

Metachronous multiple carcinomas at the site of a stoma is a rare condition after surgery. A 67-year-old man with a second tumor at the stoma site 15 years after abdominoperineal resection for rectal carcinoma is reported herein with a review of the Japanese literature. The patient visited our hospital 20 years after initial surgery, presenting with constipation and increasing tumor size in the stoma. A biopsy specimen of the tumor revealed adenocarcinoma. Block resection of the sigmoid colon and colostomy with the adjacent abdominal wall was performed. Histopathological examination showed a welldifferentiated adenocarcinoma in the stoma invading the adjacent skin. A median of 144 months from the initial operation was documented in 23 cases reported.