In Gifu city, Japan, an acute hepatitis E case occurred in 2012 (previously reported in Kanzo 55: 713-716, 2014) and another hepatitis E case occurred in 2014. Both cases developed hepatitis E after eating raw pig liver and heart at the same restaurant. The patients had no other clear risk factors for hepatitis E virus (HEV) infection. The two HEV strains were totally different, suggesting that the pig farms which provided the pig products were contaminated by different HEV strains. Japanese government issued an order forbidding restaurants to serve raw pig offal in June 2015. However, the sources and the routes of HEV infection remain unknown in most hepatitis E cases in Japan. We must still be cautious for HEV infection.
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