Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan

Shogo Shimizu; Junichi Sugihara; Yusuke Suzuki; Yoichi Nishigaki; Masaharu Takahashi; Kazuaki Takahashi; Tatsunori Nakano; Hideki Hayashi; Tomohiro Kato; Eiichi Tomita; Masahiro Arai; Hiroaki Okamoto

doi:10.2957/kanzo.56.617

Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan

Shogo Shimizu, Junichi Sugihara, Yusuke Suzuki, Yoichi Nishigaki, Masaharu Takahashi, Kazuaki Takahashi, Tatsunori Nakano, Hideki Hayashi, Tomohiro Kato, Eiichi Tomita, Masahiro Arai, Hiroaki Okamoto

Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

In Gifu city, Japan, an acute hepatitis E case occurred in 2012 (previously reported in Kanzo 55: 713-716, 2014) and another hepatitis E case occurred in 2014. Both cases developed hepatitis E after eating raw pig liver and heart at the same restaurant. The patients had no other clear risk factors for hepatitis E virus (HEV) infection. The two HEV strains were totally different, suggesting that the pig farms which provided the pig products were contaminated by different HEV strains. Japanese government issued an order forbidding restaurants to serve raw pig offal in June 2015. However, the sources and the routes of HEV infection remain unknown in most hepatitis E cases in Japan. We must still be cautious for HEV infection.

Original language	English
Pages (from-to)	617-620
Number of pages	4
Journal	Kanzo/Acta Hepatologica Japonica
Volume	56
Issue number	11
DOIs	https://doi.org/10.2957/kanzo.56.617
Publication status	Published - 04-12-2015

All Science Journal Classification (ASJC) codes

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2957/kanzo.56.617

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Shimizu, S., Sugihara, J., Suzuki, Y., Nishigaki, Y., Takahashi, M., Takahashi, K., Nakano, T., Hayashi, H., Kato, T., Tomita, E., Arai, M., & Okamoto, H. (2015). Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan. Kanzo/Acta Hepatologica Japonica, 56(11), 617-620. https://doi.org/10.2957/kanzo.56.617

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title = "Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan",

abstract = "In Gifu city, Japan, an acute hepatitis E case occurred in 2012 (previously reported in Kanzo 55: 713-716, 2014) and another hepatitis E case occurred in 2014. Both cases developed hepatitis E after eating raw pig liver and heart at the same restaurant. The patients had no other clear risk factors for hepatitis E virus (HEV) infection. The two HEV strains were totally different, suggesting that the pig farms which provided the pig products were contaminated by different HEV strains. Japanese government issued an order forbidding restaurants to serve raw pig offal in June 2015. However, the sources and the routes of HEV infection remain unknown in most hepatitis E cases in Japan. We must still be cautious for HEV infection.",

keywords = "Gifu city, Hepatitis E virus, Pig liver",

author = "Shogo Shimizu and Junichi Sugihara and Yusuke Suzuki and Yoichi Nishigaki and Masaharu Takahashi and Kazuaki Takahashi and Tatsunori Nakano and Hideki Hayashi and Tomohiro Kato and Eiichi Tomita and Masahiro Arai and Hiroaki Okamoto",

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doi = "10.2957/kanzo.56.617",

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Shimizu, S, Sugihara, J, Suzuki, Y, Nishigaki, Y, Takahashi, M, Takahashi, K, Nakano, T, Hayashi, H, Kato, T, Tomita, E, Arai, M & Okamoto, H 2015, 'Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan', Kanzo/Acta Hepatologica Japonica, vol. 56, no. 11, pp. 617-620. https://doi.org/10.2957/kanzo.56.617

TY - JOUR

T1 - Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan

AU - Shimizu, Shogo

AU - Sugihara, Junichi

AU - Suzuki, Yusuke

AU - Nishigaki, Yoichi

AU - Takahashi, Masaharu

AU - Takahashi, Kazuaki

AU - Nakano, Tatsunori

AU - Hayashi, Hideki

AU - Kato, Tomohiro

AU - Tomita, Eiichi

AU - Arai, Masahiro

AU - Okamoto, Hiroaki

PY - 2015/12/4

Y1 - 2015/12/4

N2 - In Gifu city, Japan, an acute hepatitis E case occurred in 2012 (previously reported in Kanzo 55: 713-716, 2014) and another hepatitis E case occurred in 2014. Both cases developed hepatitis E after eating raw pig liver and heart at the same restaurant. The patients had no other clear risk factors for hepatitis E virus (HEV) infection. The two HEV strains were totally different, suggesting that the pig farms which provided the pig products were contaminated by different HEV strains. Japanese government issued an order forbidding restaurants to serve raw pig offal in June 2015. However, the sources and the routes of HEV infection remain unknown in most hepatitis E cases in Japan. We must still be cautious for HEV infection.

AB - In Gifu city, Japan, an acute hepatitis E case occurred in 2012 (previously reported in Kanzo 55: 713-716, 2014) and another hepatitis E case occurred in 2014. Both cases developed hepatitis E after eating raw pig liver and heart at the same restaurant. The patients had no other clear risk factors for hepatitis E virus (HEV) infection. The two HEV strains were totally different, suggesting that the pig farms which provided the pig products were contaminated by different HEV strains. Japanese government issued an order forbidding restaurants to serve raw pig offal in June 2015. However, the sources and the routes of HEV infection remain unknown in most hepatitis E cases in Japan. We must still be cautious for HEV infection.

KW - Gifu city

KW - Hepatitis E virus

KW - Pig liver

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Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan

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