Metachronous pubic bone metastases from synchronous double cancer with prostate and ascending colon cancers: A case report

Hiroki Ito, Seiji Hishida, Tomoki Taniguchi, Daiki Kato, Manabu Takai, Koji Iinuma, Yuka Muramatsu-Maekawa, Taku Kato, Keita Nakane, Kosuke Mizutani, Tomohiro Tsuchiya, Takao Takahashi, Natuko Suzui, Tatsuhiko Miyazaki, Takuya Koie

Research output: Contribution to journalArticlepeer-review

Abstract

A 70-year-old man visited a private hospital with the chief complaint of right lower limb pain. Fluorodeoxyglucose-emission tomography (FDG-PET) showed abnormal uptake in the pubic bone, right femur, and ascending colon. The patient was referred to our hospital for further evaluation. The following tumor marker levels were found: prostate-specific antigen (PSA) 20.57 ng/ml, carcinoembryonic antigen (CEA) 108.5 ng/ml, carbohydrate antigen 19-9 (CA19-9) 1,002.1 U/ml. An open pubic bone biopsy was performed. The pathological diagnosis was metastatic adenocarcinoma from prostate cancer. Prostate and ascending colon cancers were clinically diagnosed as T2bN0Mlb and T2N0M0, respectively. Laparoscopic colectomy was performed. Androgen deprivation therapy started immediately and the serum PSA level was maintained at <0.2 ng/ml during the follow-up period. However, the CEA and CA 19-9 were higher than the normal level 2 years after the surgery. In addition, the FDG-PET revealed abnormal uptake in the pubic bone. Thus, a pubic bone biopsy was performed again. The histological diagnosis was metastatic adenocarcinoma from the ascending colon cancer. Although the patient received combination chemotherapy, he died of colon cancer.

Original languageEnglish
Pages (from-to)273-277
Number of pages5
JournalActa Urologica Japonica
Volume66
Issue number8
DOIs
Publication statusPublished - 08-2020
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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