TY - JOUR
T1 - Metastasis of osteosarcoma to stomach made clinically evident by hematemesis
T2 - A case report
AU - Urakawa, Hiroshi
AU - Tsukushi, Satoshi
AU - Tsurudome, Issei
AU - Hirata, Akihiro
AU - Arai, Eisuke
AU - Kozawa, Eiji
AU - Futamura, Naohisa
AU - Miyahara, Ryoji
AU - Ishiguro, Naoki
AU - Nishida, Yoshihiro
PY - 2013/2/26
Y1 - 2013/2/26
N2 - Background: Gastric metastasis from osteosarcoma is very rare and its clinical features are not well recognized.Case presentation: A 73-year-old man was diagnosed with osteosarcoma and treated with four cycles of preoperative chemotherapy with ifosfamide and doxorubicin followed by wide resection. Two cycles of postoperative chemotherapy with ifosfamide and doxorubicin and ten cycles of chemotherapy with carboplatin and etoposide were administered. Eleven months after the surgery, he vomited fresh blood. Unusual progression of anemia was observed with the hematemesis. A biopsy was performed by gastrointestinal endoscopy, and the stomach tumor was diagnosed as metastasis of osteosarcoma.Conclusions: Even though gastric metastasis from osteosarcoma is very rare, all three previous reports and our case showed the presence of ulcer on the surface of the gastric lesion. We should consider the possibility of gastric metastasis in patients with osteosarcoma in whom progression of anemia or gastric hemorrhage is observed.
AB - Background: Gastric metastasis from osteosarcoma is very rare and its clinical features are not well recognized.Case presentation: A 73-year-old man was diagnosed with osteosarcoma and treated with four cycles of preoperative chemotherapy with ifosfamide and doxorubicin followed by wide resection. Two cycles of postoperative chemotherapy with ifosfamide and doxorubicin and ten cycles of chemotherapy with carboplatin and etoposide were administered. Eleven months after the surgery, he vomited fresh blood. Unusual progression of anemia was observed with the hematemesis. A biopsy was performed by gastrointestinal endoscopy, and the stomach tumor was diagnosed as metastasis of osteosarcoma.Conclusions: Even though gastric metastasis from osteosarcoma is very rare, all three previous reports and our case showed the presence of ulcer on the surface of the gastric lesion. We should consider the possibility of gastric metastasis in patients with osteosarcoma in whom progression of anemia or gastric hemorrhage is observed.
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U2 - 10.1186/1477-7819-11-48
DO - 10.1186/1477-7819-11-48
M3 - Article
C2 - 23442337
AN - SCOPUS:84874201932
VL - 11
JO - World Journal of Surgical Oncology
JF - World Journal of Surgical Oncology
SN - 1477-7819
M1 - 48
ER -