TY - JOUR
T1 - Methods of estimating vancomycin use in an inpatient setting
T2 - Days of therapy versus therapeutic drug monitoring-based exposure days
AU - Murakami, Shutaro
AU - Hiroi, Junko
AU - Tokuda, Yasuharu
AU - Casabar, Ed
AU - Honda, Hitoshi
N1 - Publisher Copyright:
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Underestimating antimicrobial use based on days of therapy (DOT) is recognized for certain antimicrobial agents. We investigated the difference between DOT and therapeutic drug monitoring (TDM)-based exposure days in estimating vancomycin use and demonstrated that DOT may underestimate vancomycin exposure by ∼10%.
AB - Underestimating antimicrobial use based on days of therapy (DOT) is recognized for certain antimicrobial agents. We investigated the difference between DOT and therapeutic drug monitoring (TDM)-based exposure days in estimating vancomycin use and demonstrated that DOT may underestimate vancomycin exposure by ∼10%.
UR - http://www.scopus.com/inward/record.url?scp=85061265096&partnerID=8YFLogxK
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U2 - 10.1017/ice.2018.364
DO - 10.1017/ice.2018.364
M3 - Article
C2 - 30729904
AN - SCOPUS:85061265096
SN - 0899-823X
VL - 40
SP - 375
EP - 379
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
IS - 3
ER -
