TY - JOUR
T1 - Microscopic polyangiitis diagnosed by muscle specimen
T2 - a case report and literature review
AU - Murata, Okinori
AU - Izumi, Keisuke
AU - Kaneko, Yuko
AU - Yasuoka, Hidekata
AU - Suzuki, Katsuya
AU - Matsubara, Shiro
AU - Yamaoka, Kunihiro
AU - Takeuchi, Tsutomu
N1 - Publisher Copyright:
© 2018, © 2018 Japan College of Rheumatology.
PY - 2018/7/3
Y1 - 2018/7/3
N2 - We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.
AB - We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.
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U2 - 10.1080/24725625.2018.1429804
DO - 10.1080/24725625.2018.1429804
M3 - Article
AN - SCOPUS:85103015577
SN - 2472-5625
VL - 2
SP - 181
EP - 184
JO - Modern Rheumatology Case Reports
JF - Modern Rheumatology Case Reports
IS - 2
ER -