TY - JOUR
T1 - Microvascular Decompression for Trigeminal Neuralgia
T2 - A Prospective, Multicenter Study
AU - Mizobuchi, Yoshifumi
AU - Nagahiro, Shinji
AU - Kondo, Akinori
AU - Arita, Kazunori
AU - Date, Isao
AU - Fujii, Yukihiko
AU - Fujimaki, Takamitsu
AU - Hanaya, Ryosuke
AU - Hasegawa, Mitsuhiro
AU - Hatayama, Toru
AU - Inoue, Tooru
AU - Kasuya, Hidetoshi
AU - Kobayashi, Masahito
AU - Kohmura, Eiji
AU - Matsushima, Toshio
AU - Masuoka, Jun
AU - Morita, Akio
AU - Nishizawa, Shigeru
AU - Okayama, Yoshihiro
AU - Shigeno, Taku
AU - Shimano, Hiroshi
AU - Takeshima, Hideo
AU - Yamakami, Iwao
N1 - Publisher Copyright:
© 2021 Congress of Neurological Surgeons 2021.
PY - 2021/10/1
Y1 - 2021/10/1
N2 - BACKGROUND: Microvascular decompression (MVD) is the most effective procedure for the long-term management of trigeminal neuralgia (TGN). However, retrospective and single-center studies are inherently biased, and there are currently no prospective, multicenter studies. OBJECTIVE: To evaluate the short- and long-term outcomes and complications in patients with TGN who underwent MVD at specialized Japanese institutions. METHODS: We enrolled patients with TGN who underwent MVD between April 2012 and March 2015. We recorded their facial pain grade and complications at 7 d (short term), 1 yr (mid-term), and 3 yr (long term) postoperatively. RESULTS: There were 166 patients, comprising 60 men and 106 women (mean age 62.7 yr). Furthermore, 105 patients were aged over 60 yr. We conducted neuromonitoring in 84.3% of the cases. The complete pain relief, mortality, and complication rates at the short-term follow-up were 78.9%, 0%, and 16.3%, respectively. Overall, 155 patients (93.4%) completed the long-term follow-up, with the complete pain relief and complication rates of 80.0% and 5.2%, respectively. CONCLUSION: In the hands of experienced neurosurgeons, MVD for TGN can achieve high long-term curative effects. In addition, complications are uncommon and usually transient. Our results indicate that MVD is an effective and safe treatment for patients with TGN, including elderly patients.
AB - BACKGROUND: Microvascular decompression (MVD) is the most effective procedure for the long-term management of trigeminal neuralgia (TGN). However, retrospective and single-center studies are inherently biased, and there are currently no prospective, multicenter studies. OBJECTIVE: To evaluate the short- and long-term outcomes and complications in patients with TGN who underwent MVD at specialized Japanese institutions. METHODS: We enrolled patients with TGN who underwent MVD between April 2012 and March 2015. We recorded their facial pain grade and complications at 7 d (short term), 1 yr (mid-term), and 3 yr (long term) postoperatively. RESULTS: There were 166 patients, comprising 60 men and 106 women (mean age 62.7 yr). Furthermore, 105 patients were aged over 60 yr. We conducted neuromonitoring in 84.3% of the cases. The complete pain relief, mortality, and complication rates at the short-term follow-up were 78.9%, 0%, and 16.3%, respectively. Overall, 155 patients (93.4%) completed the long-term follow-up, with the complete pain relief and complication rates of 80.0% and 5.2%, respectively. CONCLUSION: In the hands of experienced neurosurgeons, MVD for TGN can achieve high long-term curative effects. In addition, complications are uncommon and usually transient. Our results indicate that MVD is an effective and safe treatment for patients with TGN, including elderly patients.
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U2 - 10.1093/neuros/nyab229
DO - 10.1093/neuros/nyab229
M3 - Article
C2 - 34325470
AN - SCOPUS:85116525992
SN - 0148-396X
VL - 89
SP - 557
EP - 564
JO - Neurosurgery
JF - Neurosurgery
IS - 4
ER -